European Radiology

, Volume 16, Issue 7, pp 1564–1569 | Cite as

High-resolution ex vivo imaging of coronary artery stents using 64-slice computed tomography—initial experience

  • Carsten RistEmail author
  • Konstantin Nikolaou
  • Thomas Flohr
  • Bernd J. Wintersperger
  • Maximilian F. Reiser
  • Christoph R. Becker


The aim of the study was to evaluate the potential of new-generation multi-slice computed tomography (CT) scanner technology for the delineation of coronary artery stents in an ex vivo setting. Nine stents of various diameters (seven stents 3 mm, two stents 2.5 mm) were implanted into the coronary arteries of ex vivo porcine hearts and filled with a mixture of an iodine-containing contrast agent. Specimens were scanned with a 16-slice CT (16SCT) machine; (Somatom Sensation 16, Siemens Medical Solutions), slice thickness 0.75 mm, and a 64-slice CT (64SCT, Somatom Sensation 64), slice-thickness 0.6 mm. Stent diameters as well as contrast densities were measured, on both the 16SCT and 64SCT images. No significant differences of CT densities were observed between the 16SCT and 64SCT images outside the stent lumen: 265±25HU and 254±16HU (P=0.33), respectively. CT densities derived from the 64SCT images and 16SCT images within the stent lumen were 367±36HU versus 402±28HU, P<0.05, respectively. Inner and outer stent diameters as measured from 16SCT and 64SCT images were 2.68±0.08 mm versus 2.81±0.07 mm and 3.29±0.06 mm versus 3.18±0.07 mm (P<0.05), respectively. The new 64SCT scanner proved to be superior in the ex vivo assessment of coronary artery stents to the conventional 16SCT machine. Increased spatial resolution allows for improved assessment of the coronary artery stent lumen.


Multislice CT Artefacts Stents Coronary artery 


  1. 1.
    American Heart Association (2004) Heart and stroke statistics—updateGoogle Scholar
  2. 2.
    Popma JJ, Leon MB, Moses JW, et al (2004) Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries. Circulation 110:3773–80PubMedCrossRefGoogle Scholar
  3. 3.
    Antoniucci D VR, Santoro GM, et al (1998) Restenosis after coronary stenting in current clinical practice. Am Heart J 135:510–518PubMedCrossRefGoogle Scholar
  4. 4.
    Flohr T, Stierstorfer K, Raupach R, Ulzheimer S, Bruder H (2004) Performance evaluation of a 64-slice CT system with z-flying focal spot. Rofo Fortschr Geb Rontgenstr Neuen BildgebVerfahr 176:1803–1810CrossRefGoogle Scholar
  5. 5.
    Ropers D, Baum U, Pohle K, et al (2003) Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction. Circulation 107:664–666CrossRefPubMedGoogle Scholar
  6. 6.
    Maintz D JK, Wichter T, et al (2003) Imaging of coronary artery stents using multislice computed tomography: in vitro evaluation. Eur Radiol 13:830–835PubMedGoogle Scholar
  7. 7.
    Ligabue G, Rossi R, Ratti C, Favali M, Modena MG, Romagnoli R (2004) Noninvasive evaluation of coronary artery stents patency after PTCA: role of multislice computed tomography. Radiol Med (Torino) 108:128–137Google Scholar
  8. 8.
    Mahnken AH, Buecker A, Wildberger JE, et al (2004) Coronary artery stents in multislice computed tomography: in vitro artifact evaluation. Invest Radiol 39:27–33PubMedCrossRefGoogle Scholar
  9. 9.
    Schuijf JD, Bax JJ, Jukema JW, et al (2004) Feasibility of assessment of coronary stent patency using 16-slice computed tomography. Am J Cardiol 94:427–430PubMedCrossRefGoogle Scholar
  10. 10.
    Gilard M, Cornily JC, Rioufol G, et al (2005) Noninvasive assessment of left main coronary stent patency with 16-slice computed tomography. Am J Cardiol 95:110–112PubMedCrossRefGoogle Scholar
  11. 11.
    Mahnken AH, Seyfarth T, Flohr T, et al (2005) Flat-panel detector computed tomography for the assessment of coronary artery stents: phantom study in comparison with 16-slice spiral computed tomography. Invest Radiol 40:8–13PubMedGoogle Scholar
  12. 12.
    Seifarth H, Raupach R, Schaller S, et al (2005) Assessment of coronary artery stents using 16-slice MDCT angiography: evaluation of a dedicated reconstruction kernel and a noise reduction filter. Eur Radiol 15:721–726PubMedCrossRefGoogle Scholar
  13. 13.
    Maintz D, Seifarth H, Flohr T, et al (2003) Improved coronary artery stent visualization and in-stent stenosis detection using 16-slice computed-tomography and dedicated image reconstruction technique. Invest Radiol 38:790–795PubMedGoogle Scholar
  14. 14.
    Maintz D, Grude M, Fallenberg EM, Heindel W, Fischbach R (2003) Assessment of coronary arterial stents by multislice-CT angiography. Acta Radiol 44:597–603PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Carsten Rist
    • 1
    Email author
  • Konstantin Nikolaou
    • 1
  • Thomas Flohr
    • 2
  • Bernd J. Wintersperger
    • 1
  • Maximilian F. Reiser
    • 1
  • Christoph R. Becker
    • 1
  1. 1.Department of Clinical RadiologyLudwig-Maximilians UniversityMunichGermany
  2. 2.CT DivisionSiemens Medical SolutionsForchheimGermany

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