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Low-field versus high-field MRI in diagnosing breast disorders

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Abstract

We evaluated the performance of low-field MRI in breast disorders by comparing it with high-field MRI and biopsy results. Twenty-eight consecutive patients who were able to undergo two magnetic resonance examinations on following days were examined by high-field and low-field MRI. After T1-weighted sagittal images had been obtained a dynamic 3D axial study was performed followed by the acquisition of contrast-enhanced T1-weighted sagittal images. The images were analyzed separately by two radiologists paying attention to lesion morphology and enhancement kinetics. Six patients had problems in both breasts (34 breasts studied). The results were compared with biopsy results of 27 breasts. There were 16 malignant lesions, two fibroadenomas and nine other benign lesions. The inter-magnetic-resonance-scanner κ value was 0.77 (substantial agreement), while the interobserver κ value was 0.86 and 0.81 at low and high field, respectively (excellent agreement). The sensitivity was 100 and 100%, the specificity was 82 and 73% and the accuracy was 93 and 89% at low and high field, respectively. The mean lesion size was 2 cm and the smallest malignant lesion was 8 mm in diameter. Low-field MRI is a promising tool for breast imaging. Larger materials and smaller lesions are needed to evaluate its true sensitivity and specificity.

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References

  1. Heywang SH, Wolf A, Pruss E, Hilbertz T, Eiermann W, Permanetter W (1989) MR imaging of the breast with Gd-DTPA: use and limitations. Radiology 171:95–103

    Google Scholar 

  2. Kaiser WA, Zeitler E (1989) MR imaging of the breast: fast imaging sequences with and without Gd-DTPA. Preliminary observations. Radiology 170:681–686

    CAS  PubMed  Google Scholar 

  3. Stomper PC, Herman S, Klippenstein DL et al (1995) Suspect breast lesions: findings at dynamic gadolinium-enhanced MR imaging correlated with mammographic and pathologic features. Radiology 197:387–395

    CAS  PubMed  Google Scholar 

  4. Nunes LW, Schnall MD, Orel SG et al (1997) Breast MR imaging: interpretation model. Radiology 202:833–841

    Google Scholar 

  5. Liu PF, Debatin JF, Caduff RF, Kacl G, Garzoli E, Krestin GP (1998) Improved diagnostic accuracy in dynamic contrast enhanced MRI of the breast by combined quantitative and qualitative analysis. Br J Radiol 71:501–509

    Google Scholar 

  6. Kuhl CK, Mielcareck P, Klaschik S et al (1999) Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions? Radiology 211:101–110

    CAS  PubMed  Google Scholar 

  7. Baum F, Fischer U, Vosshenrich R, Grabbe E (2002) Classification of hypervascularized lesions in CE MR imaging of the breast. Eur Radiol 12:1087–1092

    Article  CAS  PubMed  Google Scholar 

  8. Obdeijn IM, Kuijpers TJ, van Dijk P, Wiggers T, Oudkerk M (1996) MR lesion detection in a breast cancer population. J Magn Reson Imaging 6:849–854

    Google Scholar 

  9. Lee CH, Smith RC, Levine JA, Troiano RN, Tocino I (1999) Clinical usefulness of MR imaging of the breast in the evaluation of the problematic mammogram. Am J Roentgenol 173:1323–1329

    Google Scholar 

  10. Weinstein SP, Orel SG, Heller R et al (2001) MR imaging of the breast in patients with invasive lobular carcinoma. Am J Roentgenol 176:399–406

    Google Scholar 

  11. Orel SG, Schnall MD, Powell CM et al (1995) Staging of suspected breast cancer: effect of MR imaging and MR-guided biopsy. Radiology 196:115–122

    CAS  PubMed  Google Scholar 

  12. Fischer U, Kopka L, Grabbe E (1999) Breast carcinoma: effect of preoperative contrast-enhanced MR imaging on the therapeutic approach. Radiology 213:881–888

    CAS  PubMed  Google Scholar 

  13. Muuller RD, Barkhausen J, Sauerwein W, Langer R (1998) Assessment of local recurrence after breast-conserving therapy with MRI. J Comput Assist Tomogr 22:408–412

    Article  Google Scholar 

  14. Viehweg P, Heinig A, Lampe D, Buchmann J, Heywang-Kobrunner SH (1998) Retrospective analysis for evaluation of the value of contrast-enhanced MRI in patients treated with breast conservative therapy. Magma 7:141–152

    Google Scholar 

  15. Morris EA, Schwartz LH, Dershaw DD, van Zee KJ, Abramson AF, Liberman L (1997) MR imaging of the breast in patients with occult primary breast carcinoma. Radiology 205:437–440

    Google Scholar 

  16. Heywang-Kobrunner SH, Huynh AT, Viehweg P, Hanke W, Requardt H, Paprosch I (1994) Prototype breast coil for MR-guided needle localization. J Comput Assist Tomogr 18:876–881

    Google Scholar 

  17. Orel SG, Schnall MD, Newman RW, Powell CM, Torosian MH, Rosato EF (1994) MR imaging-guided localization and biopsy of breast lesions: initial experience. Radiology 193:97–102

    Google Scholar 

  18. Kuhl CK, Morakkabati N, Leutner CC, Schmiedel A, Wardelmann E, Schild HH (2001) MR imaging-guided large-core (14-gauge) needle biopsy of small lesions visible at breast MR imaging alone. Radiology 220:31–39

    Google Scholar 

  19. Ojala R, Sequeiros RB, Klemola R, Vanhala E, Jyrkinen L, Tervonen O (2002) MR-guided bone biopsy—preliminary report of a new guiding method. J Magn Reson Imaging 15:82–86

    Article  PubMed  Google Scholar 

  20. Sittek H, Perlet C, Herrman K, Linsmeier E, Kolem H, Untch M, Kessler M, Reiser M (1997) MR mammography. Preoperative marking of non-palpable breast lesions with the magnetom open at 0.2 T. Radiologe 37:685–691

    Article  Google Scholar 

  21. Palosaari K, Tervonen O (2002) Post-processing water-fat imaging technique for fat suppression in a low-field MR imaging system, evaluation in patients with rheumatoid arthritis. Magma 15:1–9

    Google Scholar 

  22. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174

    CAS  PubMed  Google Scholar 

  23. Orel SG, Schnall MD (2001) MR imaging of the breast for the detection, diagnosis and staging of breast cancer. Radiology 220:13–30

    Google Scholar 

  24. Sardanelli F, Iozelli A, Fausto A (2003) MR imaging of the breast: indications, established technique and new directions. Eur Radiol 13(Suppl 3):N28–N36

    Google Scholar 

  25. Vomweg TW, Teifke A, Kunz RP, Hintze C, Hlawatsch A, Kern A, Kreitner KF, Thelen M (2004) Combination of low and high resolution sequences in two orientations for dynamic contrast-enhanced MRI of the breast: more than a compromise. Eur Radiol 14:1732–1742

    Article  Google Scholar 

  26. Reinikainen H, Paakko E, Suramo I, Paivansalo M, Jauhiainen J, Rissanen T (2002) Dynamics of contrast enhancement in MR imaging and power Doppler ultrasonography of solid breast lesions. Acta Radiol 43:492–500

    Article  Google Scholar 

  27. Hittmair K, Turetschek K, Gomiscek G, Stiglblauer R, Schurawitzki H (1996) Field strength dependence of MRI contrast enhancement: phantom measurements and application to dynamic breast imaging. Br J Radiol 69:215–220

    Google Scholar 

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Correspondence to Eija Pääkkö.

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Pääkkö, E., Reinikainen, H., Lindholm, EL. et al. Low-field versus high-field MRI in diagnosing breast disorders. Eur Radiol 15, 1361–1368 (2005). https://doi.org/10.1007/s00330-005-2664-6

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  • DOI: https://doi.org/10.1007/s00330-005-2664-6

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