Skip to main content
Log in

Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device

  • Urogenital
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Thirty-seven consecutive patients with elevated PSA levels and negative tumor prostate biopsies underwent a MR-guided prostate biopsy in a 1.5-T scanner in the supine position. After localization of suspected tumor areas using an endorectal coil and two body-phased array coils, the biopsy device was positioned without any repositioning of the patient. The biopsy device consisted of a mount, a ball joint, a positioning stage and an insertion stage with a needle guide, which was filled with a MR-visible fluid to control positioning of the needle using a balanced steady-state free precession sequence (TrueFISP) and a high-resolution turbo spin echo (T2-TSE) sequence. Core biopsies were taken manually in the magnet. The biopsy needle could be correctly positioned in all cases. Suspected lesions with a diameter ≥10 mm could be successfully punctured. Four to nine (mean =6) biopsies were taken per patient. In 14 patients, prostate cancer was confirmed at histology. Twenty-four biopsies positive for cancer were performed in 14 patients. A correct correlation was found between the site of biopsy and histology. MR-guided prostate biopsy can be effective in increasing primary positive tumor biopsy results in patients with a history of negative tumor TRUS-guided prostate biopsies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Dennis LK, Resnick MI (2000) Analysis of recent trends in prostate cancer incidence and mortality. Prostate 42:247–252

    Article  PubMed  CAS  Google Scholar 

  2. Beyersdorff D, Winkel A, Hamm B, Lenk S, Loening StA, Taupitz M (2005) MR imaging-guided prostate biopsy with a closed MR unit at 1.5 T: Initial results. Radiology 234:576–581

    Article  PubMed  Google Scholar 

  3. Wefer AE, Hricak H, Vigneron DB, Coakley FV, Lu Y, Wefer U, Mueller-Lisse U et al (2000) Sextant localization of prostate cancer: comparison of sextant biopsy magnetic Resonance imaging and magnetized resonance spectroscopic imaging with step section histology. J Urol 164:400–404

    Article  PubMed  CAS  Google Scholar 

  4. Ikonen S, Kärkkäinen P, Kivisaari L, Salo JO, Taari K, Vehmas T, Tervahartiala P et al (1998) Magnetic resonance imaging of clinically localized prostate cancer. J Urol 159:915–919

    Article  PubMed  CAS  Google Scholar 

  5. Beyersdorff D, Taupitz M, Winkelmann B, Fischer Th, Lenk S, Loening StA, Hamm B (2002) Patients with a history of elevated prostate-specific antigen levels and negative transrectal US-guided quadrant or sextant biopsy results: value of MR imaging. Radiology 224:701–706

    Article  PubMed  Google Scholar 

  6. D’Amico AV, Schnall M, Whittington R, Malkowicz SB, Schultz D, Tomaszewski JE, Wein A (1998) Endorectal coil magnetic resonance imaging identifies locally advanced prostate cancer in select patients with clinically localized disease. Urology 51:449–454

    Article  PubMed  CAS  Google Scholar 

  7. Vilanova JC, Comet J, Capdevila A, Barcelo J, Dolz JLI, Huguet M, Barcelo C et al (2001) The value of endorectal MR imaging to predict positive biopsies in clinically intermediate-risk prostate cancer patients. Eur Radiol 11:229–235

    Article  PubMed  CAS  Google Scholar 

  8. Cruz M, Tsuda K, Narumi Y, Kuroiwa Y, Nose T, Kojima Y et al (2002) Characterization of low-intensity lesions in the peripheral zone of prostate on pre-biopsy endorectal coil MR imaging. Eur Radiol 12:357–365

    Article  PubMed  CAS  Google Scholar 

  9. Perrotti M, Han KR, Epstein RE, Kennedy EC, Rabbani F, Badani K (1999) Prospective evaluation of endorectal magnetic resonance imaging to detect tumor foci in men with prior negative prostatic biopsy: a pilot study. J Urol 162:1314–1317

    Article  PubMed  CAS  Google Scholar 

  10. Comet-Batlla J, Vilanova-Busquets JC, Saladie-Roig JM, Gelabert-Mas A, Barcelo-Vidal C (2003) The value of endorectal MRI in the early diagnosis of prostate cancer. Eur Urol 44:201–208

    Article  PubMed  Google Scholar 

  11. Engelhard K, Hollenbach HP, Deimling M, Kreckel M, Riedl C (2000) Combination of signal intensity measurements of lesions in the peripheral zone of prostate with MRI and serum PSA level for differentiating benign disease from prostate cancer. Eur Radiol 10:1947–1953

    Article  PubMed  CAS  Google Scholar 

  12. Kiessling F, Lichy M, Grobholz R, Heilmann M, Farhan N, Michel MS, Trojan L et al (2004) Simple models improve the discrimination of prostate cancers from the peripheral gland by T1-weighted dynamic MRI. Eur Radiol 14:1793–1801

    PubMed  Google Scholar 

  13. Cooksen MS et al (2000) Update on transrectal ultrasound-guided needle biopsy of the prostate. Mol Urol 4:93–97

    PubMed  Google Scholar 

  14. Uzzo RG, Wie JT, Waldbaum RS, Perlmutter AP, Byrne JC, Vaughan ED (1995) The influence of prostate size on cancer detection. J Urol 152:2304–2307

    Google Scholar 

  15. Keetch DW, Catalona WJ, Smith DS (1995) Serial prostatic biopsies in men with persistently elevated serum prostate specific antigen values. J Urol 6:1571–1574

    Google Scholar 

  16. Kimberly A, Roehl JO, Ann V, Catalona A, Catalona WJ (2002) Serial biopsy results In prostate cancer screening study. J Urol 167:2435–2439

    Article  PubMed  Google Scholar 

  17. Rørvik J, Haukaas S (2001) Magnetic resonance imaging of the prostate. Curr Opin Urol 11:181–188

    Article  PubMed  Google Scholar 

  18. Quint LE, Van Erp JS, Bland PH, Del Buono EA, Mandell StH, Grossman HB, Gikas PW (1991) Prostate cancer: correlation of MR images with tissue optical density at pathologic examination. Radiology 179:837–842

    PubMed  CAS  Google Scholar 

  19. Hata N, Jinzaki M, Kacher D, Cormak R, Gering D, Nabavi A, Silverman StG et al (2001) MR imaging-guided prostate biopsy with surgical navigation software: device validation and feasibility. Radiology 220:263–268

    PubMed  CAS  Google Scholar 

  20. Cormack RA, D’Amico AV, Hata N, Silverman S, Weinstein M, Tempany CM (2000) Feasibility of transperineal prostate biopsy under interventional magnetic resonance Guidance. Urology 56:663–664

    Article  PubMed  CAS  Google Scholar 

  21. D’Amico AV, Tempany CM, Cormack R, Hata N, Jinzaki M, Tuncali K, Weinstein M et al. (2000) Transperineal magnetic resonance image guided prostate biopsy. J Urol 104:385–387

    Article  Google Scholar 

  22. Susil RC, Camphausen K, Choyke P, Elliot R, McVeigh ER, Gustafson GS, Ning H et al (2004) System for prostate brachytherapy and biopsy in a standard 1.5-T MRI scanner. Magn Reson Med 52:683–687

    Article  PubMed  Google Scholar 

  23. Zangos ST, Eichler K, Engelmann K, Ahmed M, Dettmer S, Herzog C, Pegios W et al (2005) MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results. Eur Radiol 15:174–182

    Article  PubMed  Google Scholar 

  24. Lopez-Corona E, Ohori M, Scardino PT, Reuter VE, Gonen M, Kattan MW (2003) A Nomogram for predicting a positive repeat prostate biopsy in patients with a previous negative biopsy session. J Urol 170:1184–1188

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Engelhard.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Engelhard, K., Hollenbach, H.P., Kiefer, B. et al. Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device. Eur Radiol 16, 1237–1243 (2006). https://doi.org/10.1007/s00330-005-0100-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00330-005-0100-6

Keywords

Navigation