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CO2 as a distending medium for gastric and small bowel MRI: a feasibility study

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Abstract

This work evaluates carbon dioxide as a contrast medium for magnetic resonance imaging of the stomach and small bowel. Twelve healthy volunteers underwent rapid magnetic resonance imaging after oral administration of a carbon dioxide generating agent using a combination of breath-hold and interactive fluoroscopic imaging during breathing. Diagnostic-quality images were obtained in 100% of cases for the stomach and in 92, 75, 67 and 42% of cases for the duodenal segments 1–4, respectively. Visualisation of the jejunum and ileum proved unacceptable for clinical use and anti-peristaltic agents did not significantly influence the results. Further development of fast imaging and magnetic resonance interactive fluoroscopic methods may allow the use of carbon dioxide as a contrast medium for clinical imaging of the stomach and duodenum.

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Acknowledgements

The authors would like to thank the radiographic staff of the MRIS Unit, the Fund for Addenbrooke’s and GE Healthcare.

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Correspondence to D. J. Lomas.

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Lomas, D.J., Habib, S.H., Joubert, I.J. et al. CO2 as a distending medium for gastric and small bowel MRI: a feasibility study. Eur Radiol 15, 672–676 (2005). https://doi.org/10.1007/s00330-004-2580-1

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  • DOI: https://doi.org/10.1007/s00330-004-2580-1

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