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Rheumatology International

, Volume 20, Issue 4, pp 169–170 | Cite as

Polymyositis – an unusual manifestation of chronic graft-versus-host disease

  • Biju George
  • Debashis Danda
  • Mammen Chandy
  • Alok Srivastava
  • Vikram Mathews
Case Report

Abstract.

Polymyositis is a rare autoimmune manifestation of chronic graft-versus-host disease (GVHD) characterized by muscle pain, weakness, and an increase in muscle-related enzymes that responds well to treatment with immunosuppressive agents such as steroids and cyclosporine. We describe a case in which polymyositis was the main manifestation of chronic GVHD that occurred 12 months after allogeneic bone marrow transplantation in a patient with acute lymphocytic leukemia (ALL). The polymyositis responded well to treatment with steroids and cyclosporine, with no relapse of symptoms on tapering of the medication.

Chronic GVHD Polymyositis 

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Biju George
    • 1
  • Debashis Danda
    • 2
  • Mammen Chandy
    • 1
  • Alok Srivastava
    • 1
  • Vikram Mathews
    • 1
  1. 1.Department of Haematology, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
  2. 2.Department of Medicine and Rheumatology, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India

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