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The relation of psychological status and type D personality with central sensitization in knee osteoarthritis: everything is in your mind!

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Abstract

To evaluate the relation of psychosocial parameters and type D personality with central sensitization in knee osteoarthritis (OA). The study included 126 patients with knee OA according to the American College of Rheumatology criteria. Sociodemographic variables (age, gender, education, marital status, annual income), alcohol consumption/smoking, body mass index, comorbidities, and duration of symptoms were noted. Radiographic evaluation was performed according to the Kellgren–Lawrence grading system. The Western Ontario and McMaster Universities Osteoarthritis Index was used for clinical evaluation. Type D personality, negative affectivity, and social inhibition were evaluated using the type D Scale-14 (DS14). Central sensitization was assessed by the central sensitization inventory (CSI), while psychological status, quality of life, and sleep were assessed by the Hospital Anxiety and Depression Scale (HADS), an abbreviated version of the World Health Organization Quality of Life Instrument (WHOQOL-BREF), and the Jenkins Sleep Evaluation Scale (JSS), respectively. The effect of type D personality on study parameters including central sensitization, as well as the risk factors for the development of central sensitization were assessed by regression analyses. Patients with type D personality had higher CSI, HADS scores and lower WHOQOL-BREF scores for psychological health, social relationship, environment and general quality of life. Linear regression analysis showed that the DS14 total score has a significant positive relation with CSI (β = 0.4, p < 0.05), HADS-depression (β = 0.4, p < 0.05), HADS-anxiety (β = 0.5, p < 0.05), and HADS-total scores (β = 0.5, p < 0.05). It also had a significant negative effect on all domains of WHOQOL-BREF (p < 0.05 for all). Logistic regression analysis revealed that JSS [Odds ratio (OR) 0.83, 95% CI 0.73–0.94; p = 0.003] and negative affectivity (OR 0.78, 95% CI 0.65–0.94; p = 0.008) were independent risk factors for the development of central sensitization in knee OA. Type D personality has an impact on quality of life, central sensitization, and psychological health, with negative affectivity and sleep impairment serving as independent risk factors for central sensitization. While managing patients with knee OA, these intimate relationships should be taken into consideration.

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Data availability

The datasets gathered during the preparation of this manuscript are available from the corresponding author upon reasonable request.

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No specific funding was received from any bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article.

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Authors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Cukurova University, Adana, Turkey

    Aylin Sariyildiz, Ilke Coskun Benlidayi & Sıla Olmez Engizek

  2. Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Tarsus University, Mersin, Turkey

    Volkan Deniz

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  1. Aylin Sariyildiz
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  2. Ilke Coskun Benlidayi
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All co-authors take full responsibility for the integrity and accuracy of all aspects of the research. All authors approve the submitted version of the manuscript. Authorship contribution: conception and design of study; AS, ICB, SOE, VD. Acquisition of data; AS, ICB, SOE. Analysis and interpretation of data; AS, ICB, VD. Drafting the article or revising it critically for important intellectual content: AS, ICB, SOE, VD. Final approval of the version to be submitted: AS, ICB, SOE, VD.

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Correspondence to Ilke Coskun Benlidayi.

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The study protocol was approved by the Local Ethics Committee of the Medical Faculty (Date of approval: July 22, 2022, Number: 124/16) and the study was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Written informed consent was obtained from each study participant.

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Sariyildiz, A., Coskun Benlidayi, I., Olmez Engizek, S. et al. The relation of psychological status and type D personality with central sensitization in knee osteoarthritis: everything is in your mind!. Rheumatol Int 43, 2261–2269 (2023). https://doi.org/10.1007/s00296-023-05471-7

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