Skip to main content

Advertisement

Log in

Mapping of global research on familial Mediterranean fever: a SCI-Expanded-based bibliometric analysis

  • Observational research
  • Published:
Rheumatology International Aims and scope Submit manuscript
  • 3 Altmetric

Abstract

Background

Familial Mediterranean fever (FMF) is a disease of the innate immune system. The disease is prevalent in the Mediterranean region. A comprehensive bibliometric analysis of the published literature on FMF indexed in the SCI-Expanded is lacking.

Objective

To review the global research trend, developments, leading authors, journals, institutions, and countries, and visualization mapping of the published scientific literature on FMF.

Methods

The data were obtained from SCI-Expanded of the WoSCC database. The obtained data were analyzed using Bibliometrix: An R-tool and an online Bibliometric tool. P-value less than 0.05 was considered statistically significant.

Results

In this study, a total of 1665 publications (research article, 92% and review, 8%) on FMF were analyzed and characterized. These publications were authored by 5630 authors, and published in 465 journals. The scientific production in FMF research has been increasing over time (p < 0.0001), with scientific annual growth of 3.96%. The most frequent year of publications was 2021 (n = 98), while the most attractive and published journal in FMF research was Rheumatology International (n = 116). The leading institution was Hacettepe University. The top ranked and most cited country in FMF research was Turkey. In total, the authors’ collaboration index was 3.47.

Conclusion

Generally, FMF scientific research production has increased over the last two decades. The most studied research areas in FMF were rheumatology, general internal medicine and genetics heredity. The most studied recent trend topics in FMF research were validity, reliability, endothelial dysfunction, management, and recommendations. Moreover, regional collaboration between less active countries should be extended in order to expand FMF-related research and thus prevent and control the disease in the near future.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Sohar E, Gafni J, Pras M, Heller H (1967) Familial Mediterranean fever. A survey of 470 cases and review of the literature. Am J Med 43(2):227–253. https://doi.org/10.1016/0002-9343(67)90167-2

    Article  PubMed  CAS  Google Scholar 

  2. Lange-Sperandio B, Möhring K, Gutzler F, Mehls O (2004) Variable expression of vasculitis in siblings with familial Mediterranean fever. Pediatr Nephrol 19(5):539–543. https://doi.org/10.1007/s00467-004-1440-1

    Article  PubMed  Google Scholar 

  3. Turkish FMF Study Group (2005) Familial Mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study. Medicine 84(1):1–11. https://doi.org/10.1097/01.md.0000152370.84628.0c

    Article  Google Scholar 

  4. Daniels M, Shohat T, Brenner-Ullman A, Shohat M (1995) Familial Mediterranean fever: high gene frequency among the non-Ashkenazic and Ashkenazic Jewish populations in Israel. Am J Med Genet 55(3):311–314. https://doi.org/10.1002/ajmg.1320550313

    Article  PubMed  CAS  Google Scholar 

  5. Ozen S, Karaaslan Y, Ozdemir O, Saatci U, Bakkaloglu A, Koroglu E, Tezcan S (1998) Prevalence of juvenile chronic arthritis and familial Mediterranean fever in Turkey: a field study. J Rheumatol 25(12):2445–2449

    PubMed  CAS  Google Scholar 

  6. Onen F, Sumer H, Turkay S, Akyurek O, Tunca M, Ozdogan H (2004) Increased frequency of familial Mediterranean fever in Central Anatolia. Turkey Clin Exp Rheumatol 22(4 Suppl 34):S31–S33

    PubMed  CAS  Google Scholar 

  7. Onen F (2006) Familial Mediterranean fever. Rheumatol Int 26(6):489–496. https://doi.org/10.1007/s00296-005-0074-3

    Article  PubMed  Google Scholar 

  8. Ben-Chetrit E, Touitou I (2009) Familial Mediterranean fever in the world. Arthritis Rheum 61(10):1447–1453. https://doi.org/10.1002/art.24458

    Article  PubMed  CAS  Google Scholar 

  9. Migita K, Izumi Y, Jiuchi Y, Iwanaga N, Kawahara C, Agematsu K, Yachie A, Masumoto J, Fujikawa K, Yamasaki S, Nakamura T, Ubara Y, Koga T, Nakashima Y, Shimizu T, Umeda M, Nonaka F, Yasunami M, Eguchi K, Yoshiura K, Kawakami A (2016) Familial Mediterranean fever is no longer a rare disease in Japan. Arthritis Res Ther 18:175. https://doi.org/10.1186/s13075-016-1071-5

    Article  PubMed  PubMed Central  Google Scholar 

  10. Öztürk K, Coşkuner T, Baglan E, Sönmez HE, Yener GO, Çakmak F, Demirkan FG, Tanatar A, Karadag SG, Ozdel S, Demir F, Çakan M, Aktay Ayaz N, Sözeri B (2022) Real-life data from the largest pediatric familial Mediterranean fever cohort. Front Pediatr 9:805919. https://doi.org/10.3389/fped.2021.805919

    Article  PubMed  PubMed Central  Google Scholar 

  11. Goldfinger SE (1972) Colchicine for familial Mediterranean fever. N Engl J Med 287(25):1302. https://doi.org/10.1056/NEJM197212212872514

    Article  PubMed  CAS  Google Scholar 

  12. Zemer D, Revach M, Pras M, Modan B, Schor S, Sohar E, Gafni J (1974) A controlled trial of colchicine in preventing attacks of familial Mediterranean fever. N Engl J Med 291(18):932–934. https://doi.org/10.1056/NEJM197410312911803

    Article  PubMed  CAS  Google Scholar 

  13. Zemer D, Pras M, Sohar E, Modan M, Cabili S, Gafni J (1986) Colchicine in the prevention and treatment of the amyloidosis of familial Mediterranean fever. N Engl J Med 314(16):1001–1005. https://doi.org/10.1056/NEJM198604173141601

    Article  PubMed  CAS  Google Scholar 

  14. Ben-Zvi I, Kukuy O, Giat E, Pras E, Feld O, Kivity S, Perski O, Bornstein G, Grossman C, Harari G, Lidar M, Livneh A (2017) Anakinra for colchicine-resistant familial Mediterranean fever: a randomized, double-blind placebo-controlled trial. Arthritis Rheumatol 69(4):854–862. https://doi.org/10.1002/art.39995

    Article  PubMed  CAS  Google Scholar 

  15. Ellegaard O, Wallin JA (2015) The bibliometric analysis of scholarly production: how great is the impact? Scientometrics 105(3):1809–1831. https://doi.org/10.1007/s11192-015-1645-z

    Article  PubMed  PubMed Central  Google Scholar 

  16. Roemer RC, Borchardt R (2015) Meaningful metrics: A 21st-century librarian’s guide to bibliometrics, altmetrics, and research impact. Association of College and Research Libraries, Chicago. https://acrl.ala.org/acrlinsider/meaningful-metrics-a-21st-century-librarians-guide-to-bibliometrics-altmetrics-and-research-impact/. Accessed 01 July 2022

  17. Masri DE, Alsaayed B, Masri JE, Zreika B, Chanbour H, Salameh P (2022) Contribution of Arab countries to familial Mediterranean fever research: a PubMed-based bibliometric analysis. Rheumatol Int 42(1):95–100. https://doi.org/10.1007/s00296-021-04852-0

    Article  PubMed  Google Scholar 

  18. Kocyigit BF, Akyol A (2021) Bibliometric analysis of publication activity in the field of familial Mediterranean fever in 2010–2019: a Scopus-based study. Rheumatol Int 41(11):2015–2023. https://doi.org/10.1007/s00296-021-04988-z

    Article  PubMed  Google Scholar 

  19. Yilmaz D, Uysal HB (2017) Bibliometric analysis of the most cited first one hundred manuscripts in Familial Mediterranean fever. Meandros Med Dent J 18(2):96–107. https://doi.org/10.4274/meandros.66375

    Article  Google Scholar 

  20. Ahmad T, Tariq S, Tariq S (2022) Global research trends in Coronavirus disease 2019 (COVID-19) and hepatitis: a bibliometric analysis. J University Med Dent Coll 13(1):7–9. https://doi.org/10.37723/jumdc.v13i1.725

    Article  Google Scholar 

  21. Ahmad T, Nasir S, Musa TH, AlRyalat SAS, Khan M, Hui J (2021) Epidemiology, diagnosis, vaccines, and bibliometric analysis of the 100 top-cited studies on hepatitis E virus. Hum Vaccin Immunother 17(3):857–871. https://doi.org/10.1080/21645515.2020.1795458

    Article  PubMed  Google Scholar 

  22. Ahmad T, Murad MA, Nasir S, Musa TH, Baig M, Hui J (2021) Trends in hepatitis A research indexed in the Web of Science: a bibliometric analysis over the period from 1985 to 2019. Hum Vaccin Immunother 17(9):3221–3229. https://doi.org/10.1080/21645515.2021.1914804

    Article  PubMed  PubMed Central  Google Scholar 

  23. Haroon L-X, Ye C-X, Ahmad T, Khan M, Shah I, Su X-H, Xing L-X (2022) The 100 most cited publications in aging research: a bibliometric analysis. Electron J Gen Med 19(1):em342. https://doi.org/10.29333/ejgm/11413

    Article  Google Scholar 

  24. Idriss LT, Hussain M, Khan M, Ahmad T, Muhammad K, Baig M, Khan MM, Inamullah, (2021) Mapping of global research output in congenital cataracts from 1903 to 2021. Medicine 100(48):e27756. https://doi.org/10.1097/MD.0000000000027756

    Article  PubMed  PubMed Central  Google Scholar 

  25. Khan M, Ahmad T, Khan MM, Murad MA, Baig M, Ali A, Rehman A (2022) Research trends in polio during the last 50 years: a bibliometric analysis. J University Med Dent Coll 13(1):341–346. https://doi.org/10.37723/jumdc.v13i1.672

    Article  Google Scholar 

  26. Kwok HT, Van M, Fan KS, Chan J (2022) Top 100 cited articles in male breast cancer: a bibliometric analysis. Breast Dis 41(1):15–20. https://doi.org/10.3233/BD-201024

    Article  PubMed  Google Scholar 

  27. Rashid A, Li K, Feng Y, Ahmad T, Getaneh Y, Yu Y, Hu X, Abidi SH, Shao Y (2022) HIV-1 genetic diversity a challenge for AIDS vaccine development: a retrospective bibliometric analysis. Hum Vaccin Immunother 18(1):2014733. https://doi.org/10.1080/21645515.2021.2014733

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  28. Yeung AWK, Kulnik ST, Parvanov ED, Fassl A, Eibensteiner F, Völkl-Kernstock S, Kletecka-Pulker M, Crutzen R, Gutenberg J, Höppchen I, Niebauer J, Smeddinck JD, Willschke H, Atanasov AG (2022) Research on digital technology use in cardiology: bibliometric analysis. J Med Internet Res 24(5):e36086. https://doi.org/10.2196/36086

    Article  PubMed  PubMed Central  Google Scholar 

  29. Akyol A, Kocyigit BF (2021) Ankylosing spondylitis rehabilitation publications and the global productivity: a Web of Science-based bibliometric analysis (2000–2019). Rheumatol Int 41(11):2007–2014. https://doi.org/10.1007/s00296-021-04836-0

    Article  PubMed  Google Scholar 

  30. Kocyigit BF, Akyol A (2021) Bibliometric and altmetric analyses of publication activity in the field of behcet’s disease in 2010–2019. J Korean Med Sci 36(32):e207. https://doi.org/10.3346/jkms.2021.36.e207

    Article  PubMed  PubMed Central  Google Scholar 

  31. Akyol A, Kocyigit BF (2021) Publication activity in the field of Sjögren’s syndrome: a ten-year Web of Science based analysis. Rheumatol Int 41(4):763–769. https://doi.org/10.1007/s00296-020-04714-1

    Article  PubMed  Google Scholar 

  32. Birkle C, Pendlebury DA, Schnell J, Adams J (2020) Web of Science as a data source for research on scientific and scholarly activity. Quant Sci Stud 1(1):363–376. https://doi.org/10.1162/qss_a_00018

    Article  Google Scholar 

  33. Livneh A, Langevitz P, Zemer D, Zaks N, Kees S, Lidar T, Migdal A, Padeh S, Pras M (1997) Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum 40(10):1879–1885. https://doi.org/10.1002/art.1780401023

    Article  PubMed  CAS  Google Scholar 

  34. The International FMF Consortium (1997) Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell 90(4):797–807. https://doi.org/10.1016/s0092-8674(00)80539-5

    Article  Google Scholar 

  35. The French FMF Consortium (1997) A candidate gene for familial Mediterranean fever. Nat Genet 17(1):25–31. https://doi.org/10.1038/ng0997-25

    Article  Google Scholar 

  36. Bradford SC (1934) Sources of information on specific subjects. Engineering 137:85–86

    Google Scholar 

Download references

Acknowledgements

The author acknowledges the support of Southeast University, China for providing free online access to the WoSCC database.

Funding

This study received no funding.

Author information

Authors and Affiliations

Authors

Contributions

TA conceptualization and designed the study, conducted the search, software and formal analysis, and manuscript writing. The author is fully responsible for the integrity and accuracy of all aspects of the work.

Corresponding author

Correspondence to Tauseef Ahmad.

Ethics declarations

Conflict of interest

No potential conflict of interest related to this work has disclosed.

Compliance with ethical standards

Institutional ethical approval was not needed for this study using publicly available data.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ahmad, T. Mapping of global research on familial Mediterranean fever: a SCI-Expanded-based bibliometric analysis. Rheumatol Int 42, 2231–2239 (2022). https://doi.org/10.1007/s00296-022-05179-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-022-05179-0

Keywords

Navigation