Breastfeeding initiation, duration, and reasons for weaning in patients with systemic lupus erythematosus
- 242 Downloads
To assess breastfeeding in patients with systemic lupus erythematosus (SLE), a cross-sectional study of patients with SLE compared to a non-SLE sample was performed. Patients who had pregnancies subsequent to their diagnosis of SLE and who were followed up in the hospital were interviewed. The group of non-SLE mothers consisted of patients who had no known rheumatic disease at the time of their pregnancy, and who were approached at the hospital paediatrics service waiting room. Thirty-six pregnancies in 31 patients with SLE and the same number of non-SLE mothers were studied. The number of SLE patients who did not initiate breastfeeding was higher than that of non-SLE mothers (19.4 vs 5.6%, respectively; p 0.07). The average duration of breastfeeding in SLE patients was 6 months (SD 6 months) versus 12 months (SD 8 months) in non-SLE mothers (log rank p: 0.003). Fifty-three percent of the non-SLE mothers indicated no particular reason for weaning, and considered that they had nursed their children a suitable amount of time. Conversely, SLE patients often set weaning in motion on the grounds that they had been placed on medication (41%). However, when the treatment was analysed, in 6 out of 12 cases, it consisted of low doses of either corticosteroids or hydroxychloroquine. Patients with SLE showed reduced rates of initiating breastfeeding. They also showed reduced duration of breastfeeding, and the reason for cessation was frequently cited to be therapies which were actually of low risk. Breastfeeding duration could be optimised by improving the level of information provided to patients.
KeywordsSystemic lupus erythematosus Breastfeeding Weaning Hydroxychloroquine
Compliance with ethical standards
This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.
Conflict of interest
The authors declare no conflict of interest.
- 1.Karpouzas GA, Kitridou RC (2007) The mother in systemic lupus erythematosus. In Wallace DJ, Hahn, BH (eds) Dubois’ lupus erythematosus, 7th edn. Lippincott Williams & Wilkins, USA, pp 992–1038Google Scholar
- 2.Kavanaugh A, Cush JJ, Ahmed MS et al (2015) Proceedings from the American College of Rheumatology Reproductive Health Summit: the management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases. Arthritis Care Res 67(3):313–325Google Scholar
- 3.Andreoli L, Bertsias GK, Agmon-Levin N et al (2017) EULAR recommendations for women’s health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid síndrome. Ann Rheum Dis 76:476–485CrossRefPubMedPubMedCentralGoogle Scholar
- 9.World Health Organization. Breastfeeding health topic. Available at http://www.who.int/topics/breastfeeding/es. Accessed on 15 Jan 2016
- 15.Ministerio de Salud de la Nación, Dirección Nacional de Maternidad e Infancia. Situación de la lactancia materna en Argentina. Año 2011. Available at http://www.msal.gob.ar/images/stories/bes/graficos/0000000215cnt-a11a-Situacion-de-la-lactancia-materna-2011.pdf. Accessed on 15 Jan 2016
- 16.UNICEF ARGENTINA. Lactancia materna y su importancia en la iniciativa Maternidades Seguras y Centradas en la Familia (MSCF). Available at www.unicef.org/argentina/spanish/Informe_Argentina.pdf. Accessed on 15 Jan 2016
- 17.Available at: http://www.anmat.gov.ar/boletin_anmat/Septiembre_2011/Dispo_6556-11.pdf. Accessed on 10 Dec 2016
- 18.Available at: http://www.anmat.gov.ar/boletin_anmat/abril_2012/Dispo_2303-12.pdf. Accessed on 10 Dec 2016
- 19.Available at: http://www.ivax.com.ar/productos/Documents/SmPC/EVOQUIN.pdf. Accessed on 10 Dec 2016
- 20.Available at: http://www.trbpharma.com/site/trbinfo/cata/docs/Prospect_Polirreumin-3906-04.pdf. Accessed on 10 Dec 2016