This study aimed to determine the prevalence of rheumatoid arthritis in the United States (US) adult insured population from 2004 to 2014. This was an observational, retrospective, cross-sectional study based on US administrative health insurance claims databases (Truven Health MarketScan® Research database and IMS PharMetrics Plus database). Trends in RA prevalence focusing on the 10-year period covering January 1, 2004–December 31, 2014 were analyzed using a validated algorithm for the identification of RA. Prevalence rates in the databases were determined and age- and gender-adjusted rates were projected to the US population in 2014. Analysis of data from the two databases indicated that the RA prevalence rate in commercially insured adult US population ranged from 0.41 to 0.54% from 2004 to 2014. The prevalence varied substantially by gender and age in each year and increased gradually across the years for most subgroups. In 2014, out of 31,316,902 adult patients with continuous enrollment in the Truven Health MarketScan® Research database, 157,634 (0.50%) patients met our criteria for RA. Similarly, out of 35,083,356 adult patients in the IMS PharMetrics Plus database, 139,300 (0.50%) patients met our criteria for RA. In 2014, the overall age-adjusted prevalence of RA ranged from 0.53 to 0.55% (0.29–0.31% for males and 0.73–0.78% for females). The prevalence of RA in the US appeared to increase during the period from 2004 to 2014, affecting a conservative estimate of 1.28–1.36 million adults in 2014.
Rheumatoid arthritis Prevalence Claims databases
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Compliance with ethical standards
Conflict of interest
The authors declare that there are no potential conflicts of interest with respect to the research, authorship and/or publication of this article.
The study has been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and later amendments.
Human or animal participants
This study was a retrospective analysis of administrative claims data and does not contain any human participants or animals.
The permission from a research ethics committee was not required and formal informed consent was not obtained.
Riise T, Jacobsen BK, Gran JT (2001) Incidence and prevalence of rheumatoid arthritis in the county of Troms, northern Norway. J Rheumatol 27:1386–1389Google Scholar
Simonsson M, Bergman S, Jacobsson LT et al (1999) The prevalence of rheumatoid arthritis in Sweden. Scand J Rheumatol 28:340–343CrossRefPubMedGoogle Scholar
Symmons D, Turner G, Webb R et al (2002) The prevalence of rheumatoid arthritis in the UK: new estimates for a new century. Rheumatology (Oxford) 41:793–800CrossRefGoogle Scholar
Power D, Codd M, Ivers L et al (1999) Prevalence of rheumatoid arthritis in Dublin, Ireland: a population based survey. Ir J Med Sci 168:197–200CrossRefPubMedGoogle Scholar
Aho K, Kaipiainen-Seppänen O, Heliövaara M et al (1998) Epidemiology of rheumatoid arthritis in Finland. Semin Arthritis Rheum 27:325–334CrossRefPubMedGoogle Scholar
Gabriel SE, Crowson CS, O’Fallon WM (1999) The epidemiology of rheumatoid arthritis in Rochester, Minnesota, 1955–1985. Arthritis Rheum 42:415–420CrossRefPubMedGoogle Scholar
Simons WR, Rosenblatt LC, Trivedi DN (2012) The economic consequences of rheumatoid arthritis: analysis of Medical Expenditure Panel Survey 2004, 2005, and 2006 Data. J Occup Environ Med 54:48–55CrossRefPubMedGoogle Scholar
Helmick CG, Felson DT, Lawrence RC et al (2008) Estimates of the prevalence of arthritis and other rheumatic condition in the US. Arthritis Rheum 58:15–25CrossRefPubMedGoogle Scholar
Sacks JJ, Luo YH, Helmick CG (2010) Prevalence of specific types of arthritis and other rheumatic conditions in the ambulatory health care system in the US, 2001–2005. Arthritis Care Res 62:460–464CrossRefGoogle Scholar
Widdifield J, Labrecque J, Lix L et al (2013) Systematic review and critical appraisal of validation studies to identify rheumatic diseases in health administrative databases. Arthritis Care Res 65:1490–1503CrossRefGoogle Scholar
Lacaille D, Anis AH, Guh DP et al (2005) Gaps in care for rheumatoid arthritis: a population study. Arthritis Rheum 53(2):241–248CrossRefPubMedGoogle Scholar
Shipton D, Glazier RH, Guan J et al (2004) Effects of specialty services on disease-modifying antirhematic drug use in the treatment of rheumatoid arthritis in an insured elderly population. Med Care 42(9):907–913CrossRefPubMedGoogle Scholar
Widdifield J, Bombardier C, Bernatsky S et al (2014) An administrative data validation study of the accuracy of algorithms for identifying rheumatoid arthritis: the influence of the reference standard on algorithm performance. BMC Musculoskelet Disord 15:216CrossRefPubMedPubMedCentralGoogle Scholar
Myasoedova E, Crowson CS, Kremers HM et al (2010) Is the incidence of rheumatoid arthritis rising? Results from Olmsted County, Minnesota: 1955–2007. Arthritis Rheum 62:1576–1582CrossRefPubMedPubMedCentralGoogle Scholar
Sokka T, Kautianinen H, Pincus T et al (2010) Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study. Arthritis Res Ther 12:R42CrossRefPubMedPubMedCentralGoogle Scholar
Allaire S, Wolfe F, Niu J et al (2008) Contemporary prevalence and incidence of work disability associated with rheumatoid arthritis in the US. Arthritis Rheum 59:474–480CrossRefPubMedPubMedCentralGoogle Scholar