Abstract
Takayasu arteritis (TA) is a large vessel vasculitis involving the aorta and its major branches. Insidious inflammation usually results in gradual arterial narrowing; however, critical organ ischemia is rare. We describe a young male with TA who presented with acute mesenteric ischemia requiring intestinal resection, followed by critical limb ischemia. In our literature review, we identified intestinal gangrene as a rare manifestation of TA. However, intestinal ischemia as the first manifestation of TA has been scarcely reported in the literature. Also, ischemia of the intestine occurring together with critical limb ischemia is extremely unusual. Rheumatologists should be aware of TA as a rare cause of gastrointestinal vasculitis in young adults, which can be easily suspected by routinely examining all the peripheral pulses.
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Abbreviations
- CD:
-
Crohn’s disease
- CT:
-
Computerized tomography
- ESR:
-
Erythrocyte sedimentation rate
- GI:
-
Gastrointestinal
- HLA:
-
Human leukocyte antigen
- IgG:
-
Immunoglobulin G
- IgM:
-
Immunoglobulin M
- TA:
-
Takayasu arteritis
- UC:
-
Ulcerative colitis
- USA:
-
United States of America
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Durga Prasanna Misra, Nagarajan Krishnan, Debasis Gochhait, Dantis Emmanuel and Vir Singh Negi declare that they have no conflict of interest.
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This article does not contain any studies with human participants or animals performed by any of the authors. Standard care treatment was provided, and the patient was not part of a research study. For this type of article, formal ethical approval is not required.
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Misra, D.P., Krishnan, N., Gochhait, D. et al. Takayasu arteritis (TA) first presenting with intestinal ischemia: a case report and review of gastrointestinal tract involvement (ischemic and non-ischemic) associated with TA. Rheumatol Int 37, 169–175 (2017). https://doi.org/10.1007/s00296-016-3600-6
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DOI: https://doi.org/10.1007/s00296-016-3600-6