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A retrospective study of septic arthritis in a tertiary hospital in West Texas with high rates of methicillin-resistant Staphylococcus aureus infection

Rheumatology International volume 35, pages 1251–1256 (2015)Cite this article

Abstract

Septic arthritis is an important concern for rheumatologists in the evaluation of joint disease. Very few studies have addressed the microbiologic epidemiology and outcomes of septic arthritis in the USA since the year 2000. We performed a retrospective study of septic arthritis in a tertiary hospital in West Texas from the year 2000 to 2013. We recorded data on patient demographics, microbiologic etiology, treatment patterns, and outcomes. The most common causative organisms were Staphylococcus aureus and Streptococcus spp. Methicillin-resistant Staphylococcus aureus (MRSA) caused septic arthritis in 22.6 % of the cases. MRSA septic arthritis was associated with low rates of adequate empiric antimicrobial therapy. The mortality due to sepsis in our study was 5.5 %. Patients with septic arthritis had a mean length of stay of 13.5 ± 12.1 days and required 2.1 ± 1.4 joint operations. Many patients (29.2 %) had readmissions due to complications, and these patients had high rates of home health utilization and transfers to other facilities post hospital discharge. In our logistic regression analysis model, factors associated with poor outcomes in septic arthritis were MRSA, older age, and prosthetic joint infection. Septic arthritis is associated with significant mortality, morbidity, and health care costs, and more studies are needed to improve outcomes, especially considering the increasing rates of MRSA as the pathogen.

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Conflict of interest

All authors declare no conflict of interest.

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Affiliations

  1. Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street Bulfinch 165, Boston, MA, 02114, USA

    Sian Yik Lim

  2. Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9410, Lubbock, TX, 79430, USA

    Deepa Pannikath & Kenneth Nugent

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  1. Sian Yik Lim
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  2. Deepa Pannikath
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  3. Kenneth Nugent
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Correspondence to Sian Yik Lim.

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Lim, S.Y., Pannikath, D. & Nugent, K. A retrospective study of septic arthritis in a tertiary hospital in West Texas with high rates of methicillin-resistant Staphylococcus aureus infection. Rheumatol Int 35, 1251–1256 (2015). https://doi.org/10.1007/s00296-014-3206-9

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  • DOI: https://doi.org/10.1007/s00296-014-3206-9

Keywords

  • Septic arthritis
  • Methicillin-resistant Staphylococcus aureus
  • Outcomes
  • Epidemiology