Skip to main content

Advertisement

SpringerLink
Log in

A comparison of impact of fatigue on cognitive, physical, and psychosocial status in patients with fibromyalgia and rheumatoid arthritis

  • Original Article
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

This study was performed to compare the impact of fatigue on different aspects of quality of life in patients with rheumatoid arthritis (RA) and fibromyalgia syndrome (FM). This study involved subjects with FM (n = 45) and RA (n = 44). Impact of fatigue on physical, cognitive, and psychosocial status was measured with Fatigue Impact Scale (FIS) and health-related quality of life (HRQoL) with the Medical Outcome Study Short Form 36 (SF-36). Multiple regression analyses were used to evaluate impact of fatigue on quality of life by taking into account clinical symptoms and disease activity scores in these two patient groups. Although the severity of fatigue assessed by FSS was the same in FM and RA; according to Fatigue Impact Scale, fatigue has higher impact on cognitive function in FM (mean ± SD; 28.8 ± 19.9), and on the other hand, it has higher impact on mainly physical component (mean ± SD; 26.3 ± 4.9) in RA. Regarding all the clinical symptoms and disease activity scores, multiple regression models showed that fatigue together with pain affected the HRQoL (SF-36) in both patient groups. Fatigue has different impacts on QoL in FM and RA, respectively. Together with pain, fatigue lead FM patients to see disease as having worse health in terms of mental function, whereas it leads to poor health in terms of physical function in RA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cullen W, Kearney Y, Bury G (2002) Prevalence of fatigue in general practise. Ir J Med Sci 171:10–12

    Article  PubMed  CAS  Google Scholar 

  2. Arnold LM, Crofford LJ, Mease PJ, Burgess SM, Palmer SC, Abetz L, Martin SA (2008) Patient perspectives on the impact of fibromyalgia. Patient Educ Couns 73:114–120

    Article  PubMed  Google Scholar 

  3. Rupp I, Boshouzen HC, Jacobi CE, Dinant HJ, Andgeertrudis AM (2004) Impact of fatigue on health-related quality of life in rheumatoid arthritis. Arthr Rheum (Arthr Care Res) 51:578–585

    Article  Google Scholar 

  4. Pinals RS, Masi AT, Larsen RA (1981) Preliminary criteria for clinical remission in rheumatoid arthritis. Arthr Rheum 24:1308–1315

    Article  CAS  Google Scholar 

  5. Mease PJ, Arnold LM, Crofford LJ, Williams DA, Russell IJ, Humphrey LJ (2008) Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises. Arthr Rheum 59:952–960

    Article  Google Scholar 

  6. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS (1988) The American rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthr Rheum 31:315–324

    Article  CAS  Google Scholar 

  7. Wolfe F, Clauw DJ, Fitzcharles MA, Goldenbergrobert DL, Mease P (2010) The American College of rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthr Care Res 62(5):600–610

    Article  Google Scholar 

  8. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL et al (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the multicenter criteria committee. Arthr Rheum 33:160–172

    Article  CAS  Google Scholar 

  9. Gencay-Can A, Can SS (2012) Validation of the Turkish version of the fatigue severity scale in patients with fibromyalgia. Rheumatol Int 32(1):27–31

    Article  PubMed  Google Scholar 

  10. Armutlu K, Keser I, Korkmaz N, Akbiyik DI, Sümbüloğlu V, Güney Z, Karabudak R (2007) Psychometric study of Turkish version of Fatigue Impact Scale in multiple sclerosis patients. J Neurol Sci 255(1–2):64–68. Epub 2007 Mar 6

    Google Scholar 

  11. Ware JE Jr (2000) SF-36 health survey update. Spine 25(24):3130–3139

    Article  PubMed  Google Scholar 

  12. Fransen J, Stucki G, van Riel PCM (2003) Rheumatoid artritis measures. Arthr Rheum 214–224

  13. Creamer P, Lethbridge M, Hochberg M (1999) Determinants of pain severity in knee osteoarthritis. J Rheum 26:1785–1792

    PubMed  CAS  Google Scholar 

  14. Stebbings S, Herbison P, Doyle TCH, Treharne GJ, Highton J (2010) A comparison of fatigue correlates in rheumatoid arthritis and osteoarthritis: disparity in associations with disability, anxiety and sleep disturbance. Rheumatology 49:361–367

    Article  PubMed  Google Scholar 

  15. Kokmen E (1991) The short test of mental status. Arch Neurol 48:725–728

    Article  PubMed  CAS  Google Scholar 

  16. Hewlett S, Hehir M, Kirwan JR (2007) Measuring fatigue in rheumatoid arthritis: a systematic review of scales in use. Arthr Rheum 57:429–439

    Article  CAS  Google Scholar 

  17. Humphrey L, Arbuckle R, Mease P, Williams DA, Samsoe BD, Gilbert C (2010) Fatigue in fibromyalgia: a conceptual model informed by patient interviews. BMC Musculoskelet Disord 11:216

    Article  PubMed  Google Scholar 

  18. Martinez JE, Ferraz MB, Sato EI, Atra E (1995) Fibromyalgia versus rheumatoid arthritis: a longitudinal comparison of the quality of life. J Rheumatol 22:270–274

    PubMed  CAS  Google Scholar 

  19. Ofluoglu D, Berker N, Guven Z, Canbulat N, Yilmaz IT, Kayhan O (2005) Quality of life in patients with fibromyalgia syndrome and rheumatoid arthritis. Clin Rheumatol 24:490–492

    Article  PubMed  Google Scholar 

  20. Hewlett S, Cockshott Z, Byron M (2005) Patients’ perceptions of fatigue in rheumatoid arthritis: overwhelming, uncontrollable, ignored. Arthr Rheum 53:697–702

    Article  Google Scholar 

  21. Hewlett S, Ambler N, Almeida C, Cliss A, Hammond A, Kitchen K (2011) Self-management of fatigue in rheumatoid arthritis: a randomised controlled trial of group cognitive-behavioural therapy. Ann Rheum Dis 70:1060–1067

    Article  PubMed  Google Scholar 

  22. Wolfe F, Hawley DJ, Goldenberg DL, Russell IJ, Buskila D, Neumann L (2000) The assessment of functional impairment in fibromyalgia (FM): rasch analyses of 5 functional scales and the development of the FM health assessment questionnaire. J Rheumatol 27:1989–1999

    PubMed  CAS  Google Scholar 

  23. Smets EMA, Garssen B, Bonke B, de Haes JCJM (1995) The multidimensional fatigue ınventory (MFI): psychometric qualities of an instrument to assess fatigue. J Psychosom Res 39:315–325

    Article  PubMed  CAS  Google Scholar 

  24. Birtane M, Uzunca K, Taştekin N, Tuna H (2007) The evaluation of quality of life in fibromyalgia syndrome: a comparison with rheumatoid arthritis by using SF-36 health survey. Clin Rheumatol 26:679–684

    Article  PubMed  Google Scholar 

  25. Repping-Wuts H, Fransen J, Van Achterberg T, Bleijenberg G, Van Riel PLCM (2007) Persistent severe fatigue in patients with rheumatoid arthritis. J Clin Nurs 16:377–383

    Article  PubMed  Google Scholar 

  26. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ (1994) The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci 21:9–14

    PubMed  CAS  Google Scholar 

  27. Theander K (2004) Fatigue in patients with chronic obstructive pulmonary diseases. J Adv Nurs 45:172–177

    Article  PubMed  Google Scholar 

  28. Jones DEC, Gray JC, Newton J (2009) Perceived fatigue is comparable between different disease groups. Q J Med 102:617–624

    Article  CAS  Google Scholar 

  29. Bergman MJ, Shahouri SS, Shaver TS, Anderson JD, Weidensaul DN, Busch RE, Wang S, Wolfe F (2009) Is fatigue an inflammatory variable in rheumatoid arthritis (RA)? Analyses of fatigue in RA, osteoarthritis, and fibromyalgia. J Rheumatol 36(12):2788–2794

    Article  PubMed  Google Scholar 

  30. Hoogmoed D, Fransen J, Bleijenberg G, Riel P (2010) Physical and psychosocial correlates of severe fatigue in rheumatoid arthritis. Rheumatology 49:1294–1302

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This study was not supported in the form of grants, equipments, and drugs.

Conflict of interest

No conflict of interest is declared by authors.

Author information

Authors and Affiliations

  1. PM&R Department, İstanbul Şişli Etfal Teaching Hospital, Şişli Etfal Street, Şişli, İstanbul, Turkey

    Jülide Öncü, Fatma Başoğlu & Banu Kuran

Authors
  1. Jülide Öncü
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Fatma Başoğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Banu Kuran
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jülide Öncü.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Öncü, J., Başoğlu, F. & Kuran, B. A comparison of impact of fatigue on cognitive, physical, and psychosocial status in patients with fibromyalgia and rheumatoid arthritis. Rheumatol Int 33, 3031–3037 (2013). https://doi.org/10.1007/s00296-013-2825-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-013-2825-x

Keywords

Search

Navigation