Rheumatology International

, Volume 34, Issue 7, pp 1011–1013

Monosodium glutamate and aspartame in perceived pain in fibromyalgia

Short Communication

DOI: 10.1007/s00296-013-2801-5

Cite this article as:
Vellisca, M.Y. & Latorre, J.I. Rheumatol Int (2014) 34: 1011. doi:10.1007/s00296-013-2801-5


Our aim was to assess the effect of dietary elimination of monosodium glutamate (MSG) and aspartame on perceived pain in fibromyalgia. A total of 72 female patients with fibromyalgia were randomized to discontinuation of dietary MSG and aspartame (n = 36) or waiting list (n = 36). Patients were requested to rate their pain using a seven-point scale. Comparisons between both groups showed no significant differences on pain referred during the baseline or after the elimination of dietary MSG and aspartame. The discontinuation of dietary MSG and aspartame did not improve the symptoms of fibromyalgia.


Aspartame Diet Fibromyalgia Monosodium glutamate Pain 

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of Psychology and SociologyZaragoza UniversityTeruelSpain
  2. 2.Department of Mental HealthObispo Polanco HospitalTeruelSpain

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