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A case of brucellar monoarthritis and review of the literature

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Brucellosis is a systemic infectious disease, which constitutes a public health problem in Turkey. Brucellosis has a broad spectrum of clinical manifestations. Osteoarthicular manifestations are often seen in brucellosis but most of the brucellar monoarthritis cases are reactive rather than being septic. We report a case of brucellar (septic) monoarthritis of the knee in a 74-year-old cattleman and review of the literature.

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  1. Tanır G, Tufekci BS, Tuygun N (2009) Presentation, complications and treatment outcome of brucellosis in Turkish children. Pediatr Int 51(1):114–119

    Article  PubMed  Google Scholar 

  2. Memisoglu K, Yumuk Z, Akansel G (2008) An unusual presentation of brucellar septic arthritis involving the knee joint with extraarticular hardware: a case report. Knee 15(2):148–150

    Article  PubMed  Google Scholar 

  3. Al-Rawı ZS, Al-Khateeb N, Khalifa SJ (1987) Brucella arthritis among Iraqı patients. Br J Rheumatol 26(1):24–27

    Article  PubMed  Google Scholar 

  4. Khateeb MI, Araj GF, Majeed SA, Lulu AR (1990) Brucella arthritis: a study of 96 cases in Kuwait. Ann Rheum Dis 49:994–998

    Article  PubMed  CAS  Google Scholar 

  5. Kubler PA, Klestov AV (2001) Osteoarticular brucellosis with long latent period. Clin Rheumatol 20(6):444–446

    Article  PubMed  CAS  Google Scholar 

  6. Weil Y, Mattan Y, Liebergall M, Rahav G (2003) Brucella prosthetic joint infection; a report of 3 cases and a review of the literature. Clin Infect Dis 36(7):81–86

    Article  Google Scholar 

  7. Duyur B, Erdem HR, Ozgocmen S (2001) Paravertebral abscess formation and knee arthritis due to brucellosis in a patient with rheumatoid arthritis. Spinal Cord 39:554–556

    Article  PubMed  CAS  Google Scholar 

  8. Tassinari E, Di Motta D, Giardina F et al (2008) Brucella infection in total knee arthroplasty, case report and revision of the literature. Chir Organi Mov 92:55–59

    Article  PubMed  Google Scholar 

  9. Agarwall S, Kadhi SK, Rooney RJ (1991) Brucellosis complicating bilateral total knee arthroplasty. Clin Orthop Relat Res 267:179–181

    Google Scholar 

  10. Malizoc KN, Maleris CA, Soucacos PN (1997) Total knee arthroplasties infected by Brucella melitensis: a case report. Am J Orthop 26(4):283–285

    Google Scholar 

  11. Orti A, Roig P, Akala R et al (1997) Brucellar prosthetic arthritis in a total knee replacement. Eur J Clin Microbiol Infect Dis 16(11):843–845

    Article  PubMed  CAS  Google Scholar 

  12. Andonopoulos AP, Asımakopoulos G, Anastasiou E, Bassaris HP (1986) Brucella arthritis. Scand J Rheumatol 15(4):377–380

    Article  PubMed  CAS  Google Scholar 

  13. Yagupsky P, Peled N, Pres J (2001) Use of BACTEC 9240 blood culture system for detection of B. melitensis in synovial fluid. J Clin Microbiol 39(2):738–739

    Article  PubMed  CAS  Google Scholar 

  14. Solera J, Martinez-Alfaro E, Espinosa A (1997) Recognition and optimum treatment of brucellosis. Drugs 53(2):245–256

    Article  PubMed  CAS  Google Scholar 

  15. Ayaslıoglu N, Ozluk O, Kılıç D et al (2005) A case of brucellar septic arthritis of the knee with a prolenged clinical course. Rheumatol Int 25(1):69–71

    Article  PubMed  Google Scholar 

  16. Hashemi SH, Keramat F, Ranjbar M et al (2007) Osteoarticular complications of brucellosis in Hamedan, an endemic area in the west of Iran. Int J Infect Dis 11(6):496–500

    Article  PubMed  Google Scholar 

  17. Eder L, Zisman D, Rozenbaum M, Rosner I (2005) Clinical features and aetiology of septic arthritis in northern Israel. Rheumatology 44(12):1559–1563

    Article  PubMed  CAS  Google Scholar 

  18. Palanduz A, Telhan L, Yıldırmak Y et al (2005) Brucellar arthritis of the knee in a child. J Paediatr Child Health 41(1–2):76–77

    Article  PubMed  CAS  Google Scholar 

  19. Chen S (1990) Brucella arthritis of the knee in a young soccer player. Br J Sports Med 24(1):13

    Article  PubMed  CAS  Google Scholar 

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The authors declare that they have no conflict of interest.

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Correspondence to Ethem Turgay Cerit.

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Cerit, E.T., Aydın, M. & Azap, A. A case of brucellar monoarthritis and review of the literature. Rheumatol Int 32, 1465–1468 (2012).

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