Abstract
Patients undergoing hemodialysis therapy develop serious osteoarticular diseases. The treatment is based on prevention. The aim of our study is to determine the frequency and the associated factors to the rheumatic manifestations in hemodialysis patients. A cross-sectional study was conducted, including all hemodialysed patients in our dialysis unit. Information was obtained from patients’ symptoms, examination findings, and biological and radiological signs. The frequency of symptoms was 70% in our patients. It was proportional to the duration of hemodialysis and number of hemodialysis sessions per week. Early transplantation is of course a plausible solution, but other therapies such as improved dialysis must be considered.
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References
Brown EA, Gower PE (1982) Joint problems in patients on maintenance haemodialysis. Clin Nephrol 18:247–250
Harris SAC, Brown EA (1998) Patients surviving more than 10 years on haemodialysis. The natural history of the complications of treatment. Nephrol Dial Transplant 13:1226–1233
Kay J (2000) Osteoarticular disorders of renal origin: disease-related and iatrogenic Bailliere’s. Clin Rheumatol 14(2):285–305
Jadoul M, Garbar C, NoeÈl H et al (1997) Histologic prevalence of b2-microglobulin amyloidosis in hemodialysis: a prospective post-mortem study. Kidney Int 51(6):1928–1932
Otsubo S, Kimata N, Okutsu I, Oshikawa K, Ueda S, Sugimoto H et al (2009) Characteristics of dialysis-related amyloidosis in patients on haemodialysis therapy for more than 30 years. Nephrol Dial Transplant 24:1593–1598
Yamamoto S, Kazama JJ, Maruyama H, Nishi S, Narita I, Gejyo F (2008) Patients undergoing dialysis therapy for 30 years or more survive with serious osteoarticular disorders. Clin Nephrol 70(6):496–502
Asencio G, Rigout C, Ramperez P et al (1995) Hemodialysis-related lesions of the hand. Joint bone spine 62(4):233–240
Kuntz D, Naveau B, Bardin T et al (1984) Destructive spondyloarthropathy in hemodialysed patients: a new syndrome. Arthritis Rheum 27(4):369–375
Koda Y, Nishi S, Miyazaki S et al (1997) Switch from conventional to high-membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients. Kidney Int 52(4):1096–1101
Knudsen PJ, Leon J, Ng AK et al (1989) Hemodialysis-related induction of beta-2-microglobulin and interleukin-1 synthesis and release by mononuclear phagocytes. Nephron 53(3):188–193
Mathews M, Shen FH, Lindner A, Sherrard DJ (1980) Septic arthritis in hemodialyzed patients. Nephron 25(2):87–91
Al-Nammari SS, Gulati V, Patel R, Bejjanki N, Wright M (2008) Septic arthritis in haemodialysis patients: a seven-year multi-centre review. J Orthopaedic Surgery 16(1):54–57
Felson DT (1988) Epidemiology of hip and knee osteoarthritis. Epidemiol Rev 10:1–28
Carman WJ, Sowers MF, Howthorne VM, Weissfeld LA (1994) Obesity as a risk factor for osteoarthritis of the hand and wrist: a prospective study. Am J Epidemiol 139:119–129
Hart DJ, Doyle D, Spector TD (1995) Association between metabolic factors and knee osteoarthritis in women: the Chingford study. J Rheumatol 26:1118–1123
Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P, Levy D (1997) Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham study. Arthr Rheum 40:728–733
Michel BA, Fries JF, Bloch DA, Lane NE, Jones HH (1992) Osteophytosis of the knee: association with changes in weight bearing exercise. Clin Rheumatol 11:235–238
Panush RS, Holtz HA (1994) Is exercise good or bad for arthritis in the elderly? South Med J 87:S74–S78
Tepper S, Hochberg MC (1993) Factors associated with hip osteoarthritis: data from the first national health and nutrition examination survey (NHANES-1). Am J Epidemiol 137:1081–1088
Shiozaki H, Koga Y, Omori G, Tamaki M (1999) Obesity and osteoarthritis of the knee in women: results from the Matsudai knee osteoarthritis survey. Knee 6:189–192
Maetzel A, Makela M, Hawker G, Bombardier C (1997) Osteoarthritis of the hip and knee and mechanical occupational exposure: a systematic overview of the evidence. J Rheum 24:1599–1607
Kart-Koseoglu H, Yucel AE, Niron EA, Koseoglu H, Isiklar I, Ozdemir FN (2005) Osteoarthritis in hemodialysis patients: relationships with bone mineral density and other clinical and laboratory parameters. Rheumatol Int 25:270–275
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Akasbi, N., Houssaini, T.S., Tahiri, L. et al. Rheumatic complications of long term treatment with hemodialysis. Rheumatol Int 32, 1161–1163 (2012). https://doi.org/10.1007/s00296-010-1756-z
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DOI: https://doi.org/10.1007/s00296-010-1756-z