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Necrosis of the tongue as first symptom of Polyarteritis Nodosa (PAN): unusual presentation of a rare disease in children

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Abstract

Polyarteritis or panarteritis nodosa (PAN) is a necrotizing, focal segmental vasculitis that affects predominantly medium-sized arteries in many different organ systems. It is extremely rare in childhood. Involvement of the oral mucosa at diagnosis is uncommon in PAN. Here, we report a case of a pediatric patient with tongue necrosis.

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Authors and Affiliations

  1. Department of Pediatric Medicine, Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Piazza S. Onofrio, 4, 00135, Rome, Italy

    Paola Sabrina Buonuomo, Claudia Bracaglia, Manuela Pardeo, Andrea Campana, Antonella Insalaco, Elisabetta Cortis & Alberto G. Ugazio

  2. Department of Dermatology, Ospedale Pediatrico Bambino Gesù, Rome, Italy

    May El Hachem & Andrea Diociaiuti

  3. Unit of Pathology, Ospedale Pediatrico Bambino Gesù, Rome, Italy

    Francesco Callea

Authors
  1. Paola Sabrina Buonuomo
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  2. May El Hachem
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  3. Francesco Callea
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  4. Claudia Bracaglia
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  5. Andrea Diociaiuti
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  6. Manuela Pardeo
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  7. Andrea Campana
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  8. Antonella Insalaco
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  9. Elisabetta Cortis
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  10. Alberto G. Ugazio
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Correspondence to Paola Sabrina Buonuomo.

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Buonuomo, P.S., El Hachem, M., Callea, F. et al. Necrosis of the tongue as first symptom of Polyarteritis Nodosa (PAN): unusual presentation of a rare disease in children. Rheumatol Int 33, 1071–1073 (2013). https://doi.org/10.1007/s00296-010-1642-8

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  • DOI: https://doi.org/10.1007/s00296-010-1642-8

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