Skip to main content

Advertisement

SpringerLink
Log in

TRAF2 and cIAP2 involve in TWEAK-induced MMP-9 production in fibroblast-like synoviocytes

  • Letter to the Editor
  • Published:
Rheumatology International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Perper SJ, Browning B, Burkly LC, Weng S, Gao C, Giza K et al (2006) TWEAK is a novel arthritogenic mediator. J Immunol 177(4):2610–2620

    PubMed  CAS  Google Scholar 

  2. Kamata K, Kamijo S, Nakajima A, Koyanagi A, Kurosawa H, Yagita H et al (2006) Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis. J Immunol 177(9):6433–6439

    PubMed  CAS  Google Scholar 

  3. Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA (2003) The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. Biochem J 371(Pt 2):395–403

    Article  PubMed  CAS  Google Scholar 

  4. Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W et al (2008) IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat Cell Biol 10(11):1309–1317

    Article  PubMed  CAS  Google Scholar 

  5. Garcia-Vicuna R, Gomez-Gaviro MV, Dominguez-Luis MJ, Pec MK, Gonzalez-Alvaro I, Alvaro-Gracia JM et al (2004) CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients. Arthritis Rheum 50(12):3866–3877

    Article  PubMed  CAS  Google Scholar 

  6. Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P et al (2008) TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol 182(1):171–184

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. 1st Affiliated Hospital of China Medical University, 110001, Shenyang, China

    Liping Xia, Hui Shen, Jing Lu & Weiguo Xiao

Authors
  1. Liping Xia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hui Shen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jing Lu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Weiguo Xiao
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Weiguo Xiao.

Additional information

Supported by grant from Liaoning educational office.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Xia, L., Shen, H., Lu, J. et al. TRAF2 and cIAP2 involve in TWEAK-induced MMP-9 production in fibroblast-like synoviocytes. Rheumatol Int 32, 281–282 (2012). https://doi.org/10.1007/s00296-010-1640-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-010-1640-x

Keywords

Search

Navigation