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Transient involvement of the cerebral cortex in a flare of Behçet’s syndrome

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Abstract

We describe a flare of Behçet’s syndrome in a 42-year-old man who presented with florid mucocutaneous manifestations, headache and vomiting, but without meningeal or neurologic signs. A single, non-enhancing cortical lesion was found in the frontal lobe by computed tomography and magnetic resonance (MR) imaging studies. Diffusion-weighted analysis and MR spectroscopy were consistent with focal inflammation. The patient improved with colchicine, and after 5 months, a repeat MR scan demonstrated resolution of the inflammatory changes suggesting that involvement of the cerebral cortex may be a self-limiting phenomenon, distinct from other more frequent and destructive parenchymal manifestations of neuro-Behçet’s disease.

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Authors and Affiliations

  1. Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain, United Arab Emirates

    Walter Conca

  2. Department of Medicine, Al Ain Hospital, P.O. Box 1006, Al Ain, United Arab Emirates

    Soliman A. Kamel

  3. Division of Neurosurgery, Sheikh Khalifa Medical City, P.O. Box 51900, Abu Dhabi, United Arab Emirates

    Dominic Venne

  4. Department of Radiology, Faculty of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain, United Arab Emirates

    Peter Corr

Authors
  1. Walter Conca
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  2. Soliman A. Kamel
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  3. Dominic Venne
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  4. Peter Corr
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Correspondence to Walter Conca.

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Conca, W., Kamel, S.A., Venne, D. et al. Transient involvement of the cerebral cortex in a flare of Behçet’s syndrome. Rheumatol Int 32, 791–794 (2012). https://doi.org/10.1007/s00296-009-1362-0

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  • DOI: https://doi.org/10.1007/s00296-009-1362-0

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