Abstract
Churg–Strauss syndrome is a relapsing–remitting vasculitis that frequently involves digestive system. Ischemic perforation of the large bowel is relatively rare and potentially life threatening. We report a case treated with high dose of steroids for a relapsing of Churg–Strauss vasculopathy that underwent emergency surgery for multiple large-bowel perforations. Massive use of steroids is common for controlling relapse of this disease, but this increases the risk of intestinal perforation. A prompt switching to alternative drugs when intestinal tract is involved should be considered in order to prevent surgery.
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An erratum to this article is available at http://dx.doi.org/10.1007/s00296-015-3411-1.
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Venditti, D., Valerio, B., Ielpo, B. et al. Bowel perforations in a patient affected by Churg–Strauss syndrome under high-dose steroid treatment: will alternative drugs reduce risk of surgery?. Rheumatol Int 31, 1239–1241 (2011). https://doi.org/10.1007/s00296-009-1289-5
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DOI: https://doi.org/10.1007/s00296-009-1289-5