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Pseudo-pseudo Meigs syndrome developed under the leflunomide therapy

Rheumatology International volume 31, pages 521–523 (2011)Cite this article

Abstract

Pseudo-pseudo Meigs syndrome or Tjalma syndrome is characterized by increased CA-125 level, pleural effusion and ascites in systemic lupus erythematosus (SLE) patients without over tumor. The disorder is relatively rare and it has been reported usually in SLE patients with impaired renal functions. Herein, we present a case of a 47-year-old female patient who developed Tjalma syndrome after administration of leflunomide for rheumatoid arthritis. Surprisingly renal functions of our patient were found in normal limits. This is the first case of Tjalma syndrome that is developed in normal renal functions and the probable role of leflunomide therapy is discussed.

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Affiliations

  1. Bolu, Turkey

    Cemal Bes & Mehmet Soy

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  1. Cemal Bes
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  2. Mehmet Soy
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Correspondence to Cemal Bes.

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Bes, C., Soy, M. Pseudo-pseudo Meigs syndrome developed under the leflunomide therapy. Rheumatol Int 31, 521–523 (2011). https://doi.org/10.1007/s00296-009-1190-2

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  • DOI: https://doi.org/10.1007/s00296-009-1190-2

Keywords

  • Leflunomide
  • Tjalma syndrome
  • SLE