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Rheumatology International

, Volume 30, Issue 12, pp 1665–1668 | Cite as

Wegener’s granulomatosis presenting with life-threatening lung hemorrhage in a 7-year-old child

  • Susanna Esposito
  • Fabrizia Corona
  • Annacarla Defilippi
  • Antonella Petaccia
  • Giovanna Chidini
  • Laura Dell’Era
  • Jelena Bojanin
  • Edoardo Calderini
  • Nicola PrincipiEmail author
Case Report
  • 131 Downloads

Abstract

Wegener’s granulomatosis (WG) is an idiopathic systemic disease that usually onsets in adolescence and is rare in young children. Its diagnosis is usually based on the presence of fever with arthralgia and weight loss, associated with symptoms of upper and/or lower respiratory tract involvement and renal disorders. We describe the appearance of a life-threatening lung hemorrhage in the absence of hemoptysis in a 7-year-old girl with a completely negative previous clinical history, who was subsequently diagnosed as having WG. The teaching message is that immediate bronchoscopy with bronchoalveolar lavage seems to be advisable in the presence of severe respiratory distress and bilateral lung as well as renal involvement. When a diffuse alveolar hemorrhage syndrome is demonstrated, WG should be considered among the main etiologies even in a relatively young child without a clinically suggestive history.

Keywords

Wegener’s granulomatosis Severe respiratory distress Lung hemorrhage Crescentic glomerulonephritis 

Notes

Acknowledgments

We would like to thank the parents of the child for their conset to the publication of this report.

Conflict of interest statement

No author has any commercial or other association that might pose a conflict of interest.

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Susanna Esposito
    • 1
  • Fabrizia Corona
    • 1
  • Annacarla Defilippi
    • 1
  • Antonella Petaccia
    • 1
  • Giovanna Chidini
    • 2
  • Laura Dell’Era
    • 1
  • Jelena Bojanin
    • 1
  • Edoardo Calderini
    • 2
  • Nicola Principi
    • 1
    Email author
  1. 1.Department of Maternal and Pediatric SciencesUniversity of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina ElenaMilanItaly
  2. 2.Paediatric Intensive Care UnitFondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina ElenaMilanItaly

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