Rheumatology International

, Volume 30, Issue 12, pp 1657–1659 | Cite as

A case of the Behcet’s disease diagnosed by the panniculits after mesotherapy

  • Taner BabacanEmail author
  • Ahmet Mesut Onat
  • Yavuz Pehlivan
  • Gazi Comez
  • Ediz Tutar
Case Report


We herein report a case of 32-year-old woman who developed erythematous, indurated plaques, nodules on her lower back, hips and inguinal areas which had started after immunotherapy on the injection sites. She had a history of recurrent oral aphthous-like ulcers for 2 years and also had abdominal pain for 2 months. Colonoscopy revealed multiple aphthous ulcers on intestine. Diagnosis of lobular panniculitis was confirmed by histopathological finding of the skin biopsy and she was diagnosed as Behcet’s disease. Eruptions due to mesotherapy accepted as hypersensitivity reaction. Before employing this technique, patients should be carefully examined for Behcet’s pathognomonic clinical findings.


Mesotherapy Behcet’s disease Panniculitis 

Supplementary material

296_2009_1123_MOESM1_ESM.jpg (157 kb)
Supplementary material 1 (JPG 156 kb)
296_2009_1123_MOESM2_ESM.jpg (135 kb)
Supplementary material 2 (JPG 134 kb)
296_2009_1123_MOESM3_ESM.jpg (1.3 mb)
Supplementary material 3 (JPG 1281 kb)


  1. 1.
    Nazarro P (1966) Cutaneous manifestation of Behçet’s disease. In: Monecelli M, Nazarro P (eds) International symposium on Behçet’s disease in Rome. Karger, Basel, pp 1–24Google Scholar
  2. 2.
    International Study Group for Behcet’s Disease (1990) Criteria for diagnosis of Behcet’s disease. Lancet 335:1078–1080Google Scholar
  3. 3.
    Magro CM, Crowson AN (1995) Cutaneous manifestations of Behcet’s disease. Int J Dermatol 34:159–165CrossRefPubMedGoogle Scholar
  4. 4.
    Pistor M (1976) What is mesotherapy? Chir Dent Fr 46:59–60PubMedGoogle Scholar
  5. 5.
    Nagore E, Ramos P, Botella-Estrada R et al (2001) Cutaneous infection with Mycobacterium fortuitum after localized microinjections (mesotherapy) treated successfully with a triple drug regim. Acta Dermatol Venereol 81:291–293CrossRefGoogle Scholar
  6. 6.
    Kaneko F, Takahashi Y, Muramatsu Y et al (1985) Immunological studies on aphthous ulcer and erythema nodosum-like eruptions in Behçet’s disease. Br J Dermatol 113:303–312CrossRefPubMedGoogle Scholar
  7. 7.
    Jorizzo JL, Abermethy JL, White WL et al (1995) Mucocutaneous criteria for the diagnosis of the Behçet’s disease: an analysis of clinicopathologic data from multiple international centers. J Am Acad Dermatol 32:968–976CrossRefPubMedGoogle Scholar
  8. 8.
    O’Duffy JD, Carney JA, Deodhar S (1971) Behçet’s disease: report of 10 cases, 3 with new manifestations. Ann Int Med 75:561–570PubMedGoogle Scholar
  9. 9.
    Chun Sl, Su WPD, Lee S et al (1989) Erythema nodosum-like lesions in Behçet’s syndrome: a histopathologic study of 30 cases. J Cutan Pathol 16:259–265CrossRefPubMedGoogle Scholar
  10. 10.
    Duncan DI, Hasengschwandtner F (2005) Lipodissolve for subcutaneous fat reduction and skin retraction. Aesthet Surg J 25:530–543CrossRefPubMedGoogle Scholar
  11. 11.
    Lee DP, Chang SE (2005) Subcutaneous nodules showing fat necrosis owing to mesotherapy. Dermatol Surg 31:250–251PubMedGoogle Scholar
  12. 12.
    Rosina P, Chieregato C, Miccolis D et al (2001) Psöriasis and side-effects of mesotherapy. Int J Dermatol 40:581–583CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Taner Babacan
    • 1
    Email author
  • Ahmet Mesut Onat
    • 1
  • Yavuz Pehlivan
    • 1
  • Gazi Comez
    • 1
  • Ediz Tutar
    • 2
  1. 1.Department of Internal Medicine and RheumatologyGaziantep University School of Medicine, Sahinbey HospitalGaziantepTurkey
  2. 2.Department of PathologyGaziantep University School of Medicine, Sahinbey HospitalGaziantepTurkey

Personalised recommendations