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Portal vein thrombosis in a patient with hepatitis C virus-related cirrhosis complicated with antiphospholipid syndrome

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Abstract

We report a rare case of portal vein thrombosis (PVT) associated with antiphospholipid syndrome (APS) and hepatitis C virus-related cirrhosis. A 59-year-old woman with hepatitis C virus (HCV) infection was admitted because of coma. The blood test showed a typically cirrhosis pattern including an elevated serum ammonia level. Abdominal computed tomography showed liver cirrhosis and thrombus in the right branch of the portal vein. To elucidate the cause of PVT, antiphospholipid antibodies were examined. Both IgG anti-cardiolipin antibody (ELISA) and IgG anti-cardiolipin-β2 -glycoprotein I complex antibody (ELISA) were positive. When PVT is detected in a patient with cirrhosis, it might be necessary to examine antiphospholipid antibodies to clarify the cause of PVT.

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Authors and Affiliations

  1. Department of Internal Medicine, Kainan Municipal Hospital, 1272-3 Hikata, Kainan, 642-0002, Japan

    Yohei Kida & Yoichi Yamada

  2. Department of Health and Sport Management, Osaka University of Health and Sport Sciences, Kumatori, Japan

    Etsuko Maeshima

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  1. Yohei Kida
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  2. Etsuko Maeshima
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  3. Yoichi Yamada
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Correspondence to Yohei Kida.

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Kida, Y., Maeshima, E. & Yamada, Y. Portal vein thrombosis in a patient with hepatitis C virus-related cirrhosis complicated with antiphospholipid syndrome. Rheumatol Int 29, 1495–1498 (2009). https://doi.org/10.1007/s00296-009-0856-0

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  • DOI: https://doi.org/10.1007/s00296-009-0856-0

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