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Anaplastic large cell lymphoma presenting with symmetric polyarthritis in pregnancy

Rheumatology International volume 28, pages 909–911 (2008)Cite this article

Abstract

Anaplastic large-cell lymphoma (ALCL) is a rare T-cell lymphoma and typically is seen in children and young adults. Primary bone infiltration of ALCL is exceedingly rare. Herein we report ALCL of bone in a pregnant admitted with symmetric polyarthritis. Magnetic resonance imaging of the pelvis revealed soft tissue component of that destructive mass lesion on the right iliac crest after delivery. Excisional biopsy from the destructive mass showed anaplastic large cell lymphoma (CD 30 was positive and ALK negative). The patient was treated with combination chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP) every 4 weeks. After the third cycle of chemotherapy, a marked improvement of her arthritis and right iliac pain was noted.

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Affiliations

  1. Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, 06100, Ankara, Turkey

    Bunyamin Kisacik, Ali Akdogan, Yuksel Maras, Umut Kalyoncu, Omer Karadag & Meral Calguneri

  2. Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey

    Sadettin Kilickap

Authors
  1. Bunyamin Kisacik
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  2. Ali Akdogan
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  3. Yuksel Maras
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  4. Umut Kalyoncu
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  5. Omer Karadag
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  6. Sadettin Kilickap
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  7. Meral Calguneri
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Correspondence to Bunyamin Kisacik.

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Kisacik, B., Akdogan, A., Maras, Y. et al. Anaplastic large cell lymphoma presenting with symmetric polyarthritis in pregnancy. Rheumatol Int 28, 909–911 (2008). https://doi.org/10.1007/s00296-008-0543-6

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  • DOI: https://doi.org/10.1007/s00296-008-0543-6

Keywords

  • Lymphoma
  • Symmetric polyarthritis
  • Pregnancy