Rheumatology International

, Volume 27, Issue 9, pp 883–885 | Cite as

Psychosis leading to the diagnosis of unrecognized systemic lupus erythematosus: a case report

  • V. Fernández Ga de las HerasEmail author
  • M. A. Gorriti
  • R. García-Vicuña
  • J. L. Santos Ruiz
Case Report


We present the case of a woman whose psychiatric clinical picture was the major manifestation of SLE with unrecognized secondary antiphospholipid syndrome. The atypical onset and the subsequent clinical course of the psychiatric manifestations led to the diagnosis. This case demonstrates the heterogeneous progress of SLE, the increasing relevance of the antiphospholipid antibodies in the central nervous system and the difficulty in making an early diagnosis.


Systemic lupus erythematosus Antiphospholipid antibodies Central nervous system involvement Psychiatric symptoms 


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • V. Fernández Ga de las Heras
    • 1
    • 3
    • 4
    Email author
  • M. A. Gorriti
    • 1
  • R. García-Vicuña
    • 2
  • J. L. Santos Ruiz
    • 1
  1. 1.Department of PsychiatryLa Princesa University HospitalMadridSpain
  2. 2.Department of RheumathologyLa Princesa University HospitalMadridSpain
  3. 3.Servicio de psiquiatríaHospital de la PrincesaMadridSpain
  4. 4.Academic Unit of C and A PsychiatryImperial College LondonLondonUK

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