Rheumatology International

, Volume 27, Issue 9, pp 813–818 | Cite as

P wave dispersion in patients with rheumatoid arthritis: its relation with clinical and echocardiographic parameters

  • Hayal GulerEmail author
  • Ergun Seyfeli
  • Gunsah Sahin
  • Mehmet Duru
  • Ferit Akgul
  • Hayrettin Saglam
  • Fatih Yalcin
Original Article


P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 ± 10 years) and 27 healthy controls (mean age 47 ± 8 years) were included in the study. We performed electrocardiography and Doppler echocardiography on patients and controls. Maximum and minimum P wave duration were obtained from electrocardiographic measurements. PWD defined as the difference between maximum and minimum P wave duration was also calculated. Maximum P wave duration and PWD was higher in RA patients than controls (P = 0.031 and P = 0.001, respectively). However, there was no significant difference in minimum P wave duration between the two groups (P = 0.152). There was significant correlation between PWD and disease duration (r = 0.375, P = 0.009) and isovolumetric relaxation time (r = 0.390, P = 0.006). P wave duration and PWD was found to be higher in RA patients than healthy control subjects. PWD is closely associated with disease duration and left ventricular (LV) diastolic dysfunction.


Rheumatoid arthritis Electrocardiography P wave dispersion Atrial fibrillation Echocardiography 


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Hayal Guler
    • 1
    Email author
  • Ergun Seyfeli
    • 2
  • Gunsah Sahin
    • 3
  • Mehmet Duru
    • 4
  • Ferit Akgul
    • 2
  • Hayrettin Saglam
    • 5
  • Fatih Yalcin
    • 2
  1. 1.Department of Physical Medicine and Rehabilitation, Faculty of MedicineMustafa Kemal UniversityAntakya/HatayTurkey
  2. 2.Department of Cardiology, Faculty of MedicineMustafa Kemal UniversityHatayTurkey
  3. 3.Department of Physical Medicine and Rehabilitation, Faculty of MedicineMersin UniversityMersinTurkey
  4. 4.Department of Emergency Medicine, Faculty of MedicineMustafa Kemal UniversityHatayTurkey
  5. 5.Department of Cardiology, Faculty of MedicineAfyon Kocatepe UniversityAfyonkarahisarTurkey

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