Rheumatology International

, Volume 27, Issue 1, pp 101–102 | Cite as

Cerebellum vasculopathy and normal tension glaucoma in systemic lupus erythematosus: report of a case and review of the literature

  • Alice Y. K. Chan
  • Edmund K. Li
  • Grace L. H. Wong
  • David T. L. LiuEmail author
Case Report


Cerebellar vasculopathy is an uncommon but clinically important neuropsychiatric syndrome of systemic lupus erythematosus (NP-SLE) for its ominous outcome and need for prompt interventions. We described a young Chinese lady with systemic lupus erythematosus and normal tension glaucoma, who had sudden headache, nausea and vomiting coupled with rapid neurological deterioration leading to comatose status. Diagnosis of lupus cerebellar vasculopathy was made and intense immunosuppressive therapy consisting of prednisolone and cyclophosphamide was commenced. Clinical condition was salvaged with marked improvement of both sensorium and general well-being.


Neuropsychiatric syndromes of systemic lupus erythematosus (NP-SLE) Normal tension glaucoma Cerebellum vasculopathy 


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Alice Y. K. Chan
    • 1
  • Edmund K. Li
    • 2
  • Grace L. H. Wong
    • 2
  • David T. L. Liu
    • 3
    Email author
  1. 1.Department of HealthSocial Hygiene ServiceHong KongChina
  2. 2.Department of Medicine and Therapeutics, Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina
  3. 3.Department of Ophthalmology & Visual Sciences, Prince of Wales HospitalChinese University of Hong KongHong KongChina

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