Rheumatology International

, Volume 27, Issue 1, pp 95–96 | Cite as

Intra-articular glucocorticoid injection: an unusual cause of transient hypophosphataemia

  • Kurt C. Roberts-ThomsonEmail author
  • Guruparan Iyngkaran
  • Robert J. Fraser
Case Report


We describe a case of symptomatic hypophosphataemia following an intra-articular glucocorticoid injection.


Intra-articular Glucocorticoid Hypophosphataemia 


  1. 1.
    Oka M (1958) Absorption of acetates of hydrocortisone, (1-hydrocortisone and cortisone from the joint cavity into the circulation. J Clin Endocrinol Metab 18:755–763PubMedGoogle Scholar
  2. 2.
    Silbermann M, Moredohovich D, Toister Z, Azaria N (1978) Mechanisms involved in mandibular condylopathy secondary to intraarticular injections of glucocorticoids. J Oral Surg 36:112–117PubMedGoogle Scholar
  3. 3.
    Turner ST, Kiebzak GM, Dousa TP (1982) Mechanism of glucocorticoid effect on renal transport of phosphate. Am J Physiol 243:C227–C236PubMedGoogle Scholar
  4. 4.
    Frick A, Durasin I, Neuweg M (1984) Glucocorticoid-induced inhibition of the reabsorption of inorganic phosphate in the proximal tubule in the absence of parathyroid hormone. Adv Exp Med Biol 178:81–86PubMedGoogle Scholar
  5. 5.
    Perski M, Linsk J, Isaacs M, Jenkins JP, Rosenbluth M, Kupperman HS (1955) Acute effects of intravenous hydrocortisone on glucose and insulin tolerances and levels of serum and urinary inorganic phosphorus. J Clin Endocrinol Metab 15:1247–1252Google Scholar
  6. 6.
    Thompson JS, Palmieri GM, Eliel LP (1974) Dissociation of the lowering effect of calcitonin on plasma Ca and P in cortisone-treated nephrectomized rats. Endocrinology 94:799–802PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Kurt C. Roberts-Thomson
    • 1
    • 2
    Email author
  • Guruparan Iyngkaran
    • 1
  • Robert J. Fraser
    • 1
  1. 1.Department of MedicineRoyal Adelaide HospitalAdelaideAustralia
  2. 2.Department of CardiologyRoyal Melbourne HospitalParkvilleAustralia

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