Skip to main content

Advertisement

Log in

A case of hepatocellular carcinoma who admitted with Raynaud’s phenomenon

  • Case Report
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

Hepatocellular carcinoma (HCC) may be present in one of the several ways. The classical presentation is with right upper quadrant abdominal pain, abdominal swelling and weight loss. HCC may also be associated with several paraneoplastic manifestations. The mechanisms of these manifestations are not well known. The association of digital ischemia and malignancy was reported as early as 1884 and 1891. We report a case of HCC associated with Raynaund’s phenomenon.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. O’Connor B (1884) Symmetrical gangrene. Br Med J 1:460

    Google Scholar 

  2. Pagge CH, Pye-Smith PH. Textbook of principles and practice of medicine, vol 2, 3rd edn. London J&A Churchill, 1891:118

  3. Bisceglie AM (1999) Malignant neoplasm of the liver. In: Schiff ER, Sorreil MF, Maddrey WC (eds.). Schifl disease of the liver, vol 2. 8th edn. Lippincott Williams and Wilkins, Philadelphia, pp 1281–1304

  4. Pasteur W, Price-Jones C (1901) A case of cancer of stomach, with unusual vascular and blood changes. Trans Clin Soc Lond 34:160–164

    Google Scholar 

  5. Hamilton WF (1920) Carcinoma of oesophagus and Raynaud’s disease. Can Med Assoc J 1:670–671

    Google Scholar 

  6. Bennet Tl, Poulton EP (1928) Raynaud’s disease associated with cancer of the stomach. Am J Med Sci 176:654–657

    Article  Google Scholar 

  7. Domz CA, Chapman CG (1961) Pseudo-Raynaud’s; cryoglobulinemia secondary to occult neoplasm. Calif Med 95:391–393

    PubMed  CAS  Google Scholar 

  8. De Cross M (1992) Paraneoplastic Raynaud’s phenomenon. Am J Med 92:571–572

    Article  Google Scholar 

  9. Prescott RJ, Fremaont AJ, Jones et al (1992) Sequential dermal microvascular and perivascular changes in the development of scleroderma. J Pathol 166:255–263

    Article  PubMed  CAS  Google Scholar 

  10. Zignego AL, Brechot C (1999) Extrahepatic manifestations of HCV infection: facts and controversies. J Hepatol 31:369–376

    Article  PubMed  CAS  Google Scholar 

  11. Gorevic PD, Kassab HY, Levo Y et al (1980) Mixed cryoglobulinemia: clinical aspects and long term follow-up of 40 patients. Am J Med 287:69–75

    Google Scholar 

  12. McMurray RW (1998) Hepatitis C associated autoimmune disorders. Rheum Dis Clin 24:353–374

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Cem Sahan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sahan, C., Ucer, T. & Aksakal, E. A case of hepatocellular carcinoma who admitted with Raynaud’s phenomenon. Rheumatol Int 27, 87–89 (2006). https://doi.org/10.1007/s00296-006-0154-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-006-0154-z

Keywords

Navigation