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A primary Sjögren’s syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis

Report of a case study and review of the literature

Rheumatology International volume 26, pages 86–89 (2005)Cite this article

Abstract

Although renal tubular acidosis (RTA), secondary to autoimmune interstitial nephritis, develops in a large proportion of patients with Sjögren’s syndrome (SS), most of the subjects are asymptomatic. Here, we shall present a 39-year-old female patient who came to us with hypokalemic periodic paralysis (HPP), and who was later diagnosed with distal RTA. The patient, who had xerostomia and xerophthalmia for a long period of time, was diagnosed with primary SS from serologic and histologic findings. The patient recovered by being prescribed potassium replacement therapy. Although renal biopsy was not performed, corticosteroids were administered because HPP indicated severe interstitial nephritis. HPP did not reoccur during a 2-year follow-up period. We also review cases with SS-related distal RTA and HPP.

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Author information

Affiliations

  1. Department of Rheumatology, Trakya Medical Faculty, University of Trakya, Edirne, Turkey

    Mehmet Soy & Ömer Nuri Pamuk

  2. Department of Internal Medicine, Trakya Medical Faculty, University of Trakya, Edirne, Turkey

    Murat Gerenli

  3. Department of Neurology, Trakya Medical Faculty, University of Trakya, Edirne, Turkey

    Yahya Çelik

  4. Trakya Üniversitesi Tıp Fakültesi, Romatoloji Bilim Dalı, Edirne, Turkey

    Mehmet Soy

Authors
  1. Mehmet Soy
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  2. Ömer Nuri Pamuk
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  3. Murat Gerenli
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  4. Yahya Çelik
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Correspondence to Mehmet Soy.

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Soy, M., Pamuk, Ö.N., Gerenli, M. et al. A primary Sjögren’s syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis. Rheumatol Int 26, 86–89 (2005). https://doi.org/10.1007/s00296-005-0587-9

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  • DOI: https://doi.org/10.1007/s00296-005-0587-9

Keywords

  • Sjögren’s syndrome
  • Renal tubular acidosis
  • Hypokalemic periodic paralysis
  • Interstitial nephritis
  • Xerostomia
  • Xerophthalmia