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Impact of pain severity and location on health-related quality of life

Rheumatology International volume 26, pages 567–572 (2006)Cite this article

Abstract

Despite evidence that persistent pain affects well-being, little is known about the relationship of the location of pain to psychological and functional well-being. To determine whether patients with musculoskeletal disorders (MSD) are more likely to be depressed and functionally disabled compared to patients with pain at other sites, we conducted a secondary data analysis of the Medical Outcome Study—an observational study of adult outpatients with chronic medical conditions. Of the 3,360 patients who completed the baseline assessment, 1,237 (36.8%) had MSD and 2,123 (63.2%) had no MSD. Among patients in the MSD group, 84.5% reported ≥mild pain as compared to 70% in the no MSD. In multivariate analyses, MSD patients were more likely than non-MSD patients to be depressed (β coefficient=−1.9, p=0.008) and functionally disabled (β coefficient=−4.4, p<0.0001). However, the impact of MSD was eliminated after controlling for pain severity. Regardless of the location of pain, pain severity appears to be an important correlate of functional status, both mental and physical.

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Author information

Affiliations

  1. Division of Rheumatology, Indiana University School of Medicine, 1110 West Michigan Street,  , IN, 46202-5100, USA

    Dennis C. Ang

  2. Division of General Internal Medicine and Geriatrics, Regenstrief Institute Inc., Indiana University School of Medicine, Indianapolis, IN, USA

    Kurt Kroenke & Colleen A. McHorney

  3. HSR&D Program at the Roudebush VAMC, Indianapolis, IN, USA

    Colleen A. McHorney

Authors
  1. Dennis C. Ang
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  2. Kurt Kroenke
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  3. Colleen A. McHorney
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Correspondence to Dennis C. Ang.

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Ang, D.C., Kroenke, K. & McHorney, C.A. Impact of pain severity and location on health-related quality of life. Rheumatol Int 26, 567–572 (2006). https://doi.org/10.1007/s00296-005-0025-z

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  • DOI: https://doi.org/10.1007/s00296-005-0025-z

Keywords

  • Musculoskeletal disorders
  • Chronic pain
  • Depression
  • Physical function
  • Observational study