Skip to main content
SpringerLink
Log in

Cold-sensitive rad52 alleles of yeast

  • ORIGINAL PAPER
  • Published:
Current Genetics Aims and scope Submit manuscript

Abstract

We have characterized two rad52 mutations that are cold-sensitive for growth on MMS agar. The mutations change residues 61 and 69, respectively, in the 504 amino-acid open reading frame. Neither mutation has a profound effect on mitotic crossing-over or on gene conversion. One has a severe deficiency in sporulation at all temperatures, while the other has a partial deficiency and reduced spore viability. Both mutants are retarded in growth on MMS agar by a high-copy plasmid expressing RAD51.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Minnesota, 435 Delaware St. SE, Minneapolis, MN 55455-0347, USA, , , , , , US

    Minh M. Nguyen & D. M. Livingston

Authors
  1. Minh M. Nguyen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. M. Livingston
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 18 April / 14 May 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nguyen, M., Livingston, D. Cold-sensitive rad52 alleles of yeast. Curr Genet 32, 100–107 (1997). https://doi.org/10.1007/s002940050253

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s002940050253

Search

Navigation