Abstract
Bacterial actin MreB is required for the maintenance of cell polarity. MreB is located underneath the cell membrane and mainly localizes at a central cylindrical part of the cell. In addition, it has recently been found that anionic phospholipids (aPLs: phosphatidylglycerol and cardiolipin) play a crucial role in excluding MreB from the cell poles. Subcellular localization of MreB is positively and negatively regulated by membrane curvature and aPLs, respectively.
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10 May 2017
An erratum to this article has been published.
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Acknowledgements
I am grateful to Dr. Hironori Niki (National Institute of Genetics, Japan) for critically reading the manuscript and thank my lab members for their work. Work in my laboratory was supported by JSPS KAKENHI (Grant Nos. 24770191, 25117528, 15H01333, and 15H04731) and the NIG Collaborative Research Program (2013-B9, 2014-A50, 2015-B5, and 2016-A1 (40)).
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Communicated by M. Kupiec.
An erratum to this article is available at https://doi.org/10.1007/s00294-017-0701-z.
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Shiomi, D. Polar localization of MreB actin is inhibited by anionic phospholipids in the rod-shaped bacterium Escherichia coli . Curr Genet 63, 845–848 (2017). https://doi.org/10.1007/s00294-017-0696-5
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DOI: https://doi.org/10.1007/s00294-017-0696-5