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RETRACTED ARTICLE: The exocyst in Candida albicans polarized secretion and filamentation

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This article was retracted on 03 October 2016

Abstract

The exocyst is an octameric complex that orchestrates the docking and tethering of vesicles to the plasma membrane during exocytosis and is fundamental for key biological processes including growth and establishment of cell polarity. Although components of the exocyst are well conserved among fungi, the specific functions of each component of the exocyst complex unique to Candida albicans biology and pathogenesis are not fully understood. This commentary describes recent findings regarding the role of exocyst subunits Sec6 and Sec15 in C. albicans filamentation and virulence.

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Acknowledgments

This work was supported by funding from the Department of Veterans’ Affairs (Merit Award 5I01BX001130 to SAL), Biomedical Research Institute of New Mexico (SAL), NIH Grant T32AI007538 (SMB), NIH Grant K12GM088021 (ASERT/IRACDA to AAC-D) and NIH Grant 5 T32 AI007538-13 (AAC-D).

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Authors and Affiliations

  1. Section of Infectious Diseases, New Mexico VA Healthcare System, 1501 San Pedro SE, Mail Code 111-J, Albuquerque, NM, 87108, USA

    Alba A. Chavez-Dozal, Stella M. Bernardo & Samuel A. Lee

  2. Division of Infectious Diseases, University of New Mexico Health Science Center, Albuquerque, NM, 87131, USA

    Alba A. Chavez-Dozal, Stella M. Bernardo & Samuel A. Lee

Authors
  1. Alba A. Chavez-Dozal
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  2. Stella M. Bernardo
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  3. Samuel A. Lee
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Corresponding author

Correspondence to Alba A. Chavez-Dozal.

Additional information

Communicated by M. Kupiec.

The authors and the journal hereby retract this article. The authors have stated that the manuscript contains fictitious data. Two articles also published by the authors (Chavez-Dozal 2015a; Chavez-Dozal et al., 2015), which mainly formed the basis for this review article, have meanwhile been retracted, because they contained several images with fabricated or falsified data. AA Chavez-Dozal did not respond when asked to agree to the retraction.

An erratum to this article can be found online at http://dx.doi.org/10.1007/s00294-016-0655-6.

An erratum to this article can be found at http://dx.doi.org/10.1007/s00294-016-0655-6.

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Chavez-Dozal, A.A., Bernardo, S.M. & Lee, S.A. RETRACTED ARTICLE: The exocyst in Candida albicans polarized secretion and filamentation. Curr Genet 62, 343–346 (2016). https://doi.org/10.1007/s00294-015-0553-3

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  • DOI: https://doi.org/10.1007/s00294-015-0553-3

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