Current Genetics

, Volume 61, Issue 4, pp 489–492 | Cite as

Bacterial histone-like proteins: roles in stress resistance

  • Ge Wang
  • Robert J. MaierEmail author


Histone-like proteins (HLPs) are small and basic bacterial proteins that are associated with a nucleoid and play roles in maintaining DNA architecture and regulating DNA transactions such as replication, recombination/repair and transcription. The studies on HLPs from a variety of bacterial species in recent years are summarized in this mini-review. A recent study reported a novel DNA-binding protein (HP119) in Helicobacter pylori that shows some HLP features. It plays a large role in aiding bacterial stress resistance. We provide herein additional evidence that HP119 is a nucleoid-associated protein, and present some perspectives for future study.


Histone-like proteins Helicobacter pylori Stress resistance 



This work was supported by The University of Georgia Research Foundation.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of MicrobiologyUniversity of GeorgiaAthensUSA

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