Skip to main content
SpringerLink
Log in

Grading von Prostatakarzinomen

Grading of prostate cancer

  • Schwerpunkt: Grading-Systeme
  • Published:
Der Pathologe Aims and scope Submit manuscript

Zusammenfassung

Das derzeitige Grading von Prostatakarzinomen beruht auf dem Graduierungssystem der Internationalen Gesellschaft für Uropathologie (ISUP) nach einer Konsensuskonferenz in Chicago 2014. Die Grundlage hierzu bildete das mehrfach modifizierte Gradingsystem von Gleason. Im vorliegenden Beitrag wird die Entwicklung zum heutigen ISUP-Grading kurz dargestellt.

Abstract

The current grading of prostate cancer is based on the classification system of the International Society of Urological Pathology (ISUP) following a consensus conference in Chicago in 2014. The foundations are based on the frequently modified grading system of Gleason. This article presents a brief description of the development to the current ISUP grading system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1

Literatur

  1. Epstein JI, Allsbrook WC, Amin MB, Egevad L, the ISUP grading committee (2005) The 2005 International Society of Urological Pathology (ISUP) consensus conference on Gleason Grading of prostatic carcinoma. Am J Surg Pathol 29:1228–1249

    Article  PubMed  Google Scholar 

  2. Epstein JI (2010) An update of the Gleason Grading System. J Urol 183:433–440

    Article  PubMed  Google Scholar 

  3. Epstein JI, Egevad LO, Amin MB et al (2016) The 2014 International Society of Urological Pathology (ISUP) consensus conference on Gleason grading of prostatic carcinoma: Definition of grading patterns and proposal for a new grading system. Am J Surg Pathol 40:244–252

    PubMed  Google Scholar 

  4. Gleason DF (1966) Classification of prostatic carcinomas. Cancer Chemother Rep 50:125–136

    CAS  PubMed  Google Scholar 

  5. Helpap B, Ringli D, Breul J et al (2015) The value of prognostic grouping of prostatic carcinomas for urologists and pathologists. Urol Int 95:436–444

    Article  CAS  PubMed  Google Scholar 

  6. Helpap B, Bubendorf L, Kristiansen G (2016) Prostatakarzinom Teil 2: Rückblick über die verschiedenen Tumorgradingverfahren der Jahre 1966–2015 und Zukunftsperspektiven des neuen Gradings der International Society of Urological Pathology (ISUP). Pathologe 37:11–16

    Article  CAS  PubMed  Google Scholar 

  7. Kristiansen G, Egevad L, Amin M et al (2016) Konsensuskonferenz 2014 der ISUP zur Gleason-Graduierung des Prostatakarzinoms. Pathologe 37:17–26

    Article  CAS  PubMed  Google Scholar 

  8. Moch H, Humphrey PA, Ulbright TM et al (2016) WHO Classification of tumours of the urinary system and male genital organs. WHO Press, Geneva

    Google Scholar 

  9. Pierorazio PM, Walsh PC, Partin AW, Epstein JI (2013) Prognostic Gleason grade grouping: data based on the modified Gleason scoring system. BJU Int 111:753–760

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Pathologie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland

    G. Kristiansen

  2. Institut für Pathologie, Universität Mainz, Mainz, Deutschland

    W. Roth

  3. Institut für Pathologie, Hegau-Bodensee-Kliniken, Akademisches Lehrkrankenhaus der Universität Freiburg, Postfach 720, 78207, Singen, Deutschland

    B. Helpap

Authors
  1. G. Kristiansen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. Roth
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. Helpap
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to G. Kristiansen.

Ethics declarations

Interessenkonflikt

G. Kristiansen, W. Roth und B. Helpap geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Additional information

Schwerpunktherausgeber

C. Wittekind, Leipzig

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kristiansen, G., Roth, W. & Helpap, B. Grading von Prostatakarzinomen. Pathologe 37, 352–354 (2016). https://doi.org/10.1007/s00292-016-0185-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00292-016-0185-5

Schlüsselwörter

Keywords

Search

Navigation