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Intraoperativer Gefrierschnitt der Schilddrüse

Intraoperative frozen sections of the thyroid gland

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Zusammenfassung

Der intraoperative Gefrierschnitt der Schilddrüse hat das Ziel, in kürzestmöglicher Zeit eine definitive Diagnose, die das weitere operative Management bestimmt, zu erhalten. Aufgrund der Besonderheiten der intraoperativen Diagnostik von Schilddrüsenläsionen ist eine bereits intraoperativ definitive Diagnose jedoch nur bei einem Teil der Fälle möglich. Falls intraoperativ keine definitive Diagnose gestellt werden kann, gelingt durch entsprechend bevorzugte Bearbeitung des Materials mit wenigen Ausnahmen eine abschließende Diagnosestellung spätestens innerhalb von 48 h. Diese Vorgehensweise setzt beim Pathologen und Chirurgen ein hohes Maß an Kommunikation und Kenntnis der Besonderheiten der Diagnostik und Therapie insbesondere von Schilddrüsenmalignomen voraus, da in Abhängigkeit vom histologischen Tumortyp unterschiedliche Operationsstrategien verfolgt werden.

Abstract

The goal of evaluation of intraoperative frozen sections of the thyroid gland is to achieve a definitive diagnosis which determines the subsequent surgical management as fast as possible; however, due to the specific methodological situation of thyroid frozen sections evaluation a conclusive diagnosis can be made in only some of the cases. If no conclusive histological diagnosis is possible during the operation, subsequent privileged processing of the specimen allows a final diagnosis at the latest within 48 h in almost all remaining cases. Applying this strategy, both pathologists and surgeons require a high level of communication and knowledge regarding the specific diagnostic and therapeutic peculiarities of thyroid malignancies because different surgical strategies must be employed depending on the histological tumor subtype.

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Authors and Affiliations

  1. Institut für Pathologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Deutschland

    S. Synoracki, S. Ting &  K. W. Schmid

  2. Institut für Pathologie, Universitätsklinikum Halle/Saale, Martin-Luther Universität Halle-Wittenberg, Halle (Saale), Deutschland

    U. Siebolts

  3. Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Universitätsklinikum Halle/Saale, Martin-Luther Universität Halle-Wittenberg, Halle (Saale), Deutschland

    H. Dralle

  4. Institut für Pathologie, Medizinische Universität Wien, Wien, Österreich

    O. Koperek

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  1. S. Synoracki
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  2. S. Ting
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  3. U. Siebolts
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  4. H. Dralle
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  6. K. W. Schmid
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Correspondence to K. W. Schmid.

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S. Synoracki, S. Ting, U. Siebolts, H. Dralle, O. Koperek und K.W. Schmid geben an, dass kein Interessenkonflikt besteht.

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Synoracki, S., Ting, S., Siebolts, U. et al. Intraoperativer Gefrierschnitt der Schilddrüse. Pathologe 36, 362–371 (2015). https://doi.org/10.1007/s00292-015-0038-7

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  • DOI: https://doi.org/10.1007/s00292-015-0038-7

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