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Eosinophile Ösophagitis

Die Sicht des Gastroenterologen

Eosinophilic esophagitis

The gastroenterologist’s perspective

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Zusammenfassung

Die eosinophile Ösophagitis ist charakterisiert durch Symptome ösophagealer Dysfunktion (meist Dysphagie) und eosinophile Entzündungsinfiltrate im Ösophagus. Diese kommen in anderen Abschnitten des Gastrointestinaltrakts nicht vor. Differenzialdiagnosen, die mit ösophagealer Eosinophilie einhergehen, müssen vor der Diagnose einer eosinophilen Ösophagitis ausgeschlossen werden. Der typische Patient mit eosinophiler Ösophagitis ist männlich und hat atopische Begleiterkrankungen. Zu den Behandlungsoptionen gehören medikamentöse Therapie, Eliminationsdiät sowie ösophageale Dilatation.

Abstract

Eosinophilic esophagitis is characterized by symptoms of esophageal dysfunction and eosinophil-predominant esophageal inflammation. Eosinophilic inflammation in other parts of the gastrointestinal tract is absent and several differential diagnoses for esophageal eosinophilia have to be excluded before diagnosing eosinophilic esophagitis. Most patients are male and have concomitant atopic disorders. Therapeutic options are based on drugs, diet and dilation.

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Danksagung

Die vorliegende Arbeit wurde durch ein Stipendium des Schweizerischen Nationalfonds zugunsten des Autors ermöglicht (SNF grant Nummer 32003B_135665/1).

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Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Correspondence to A. Schoepfer.

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Schoepfer, A. Eosinophile Ösophagitis. Pathologe 33 (Suppl 2), 225–227 (2012). https://doi.org/10.1007/s00292-012-1643-3

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  • DOI: https://doi.org/10.1007/s00292-012-1643-3

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