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Undifferenzierte Pankreaskarzinome

Der Sprung ins Chaos

Undifferentiated pancreatic carcinomas

Leap into chaos

Zusammenfassung

Die undifferenzierten Karzinome des Pankreas sind selten. Sie sind anaplastische Varianten des duktalen Adenokarzinoms des Pankreas. Differenzialdiagnostisch müssen sie von Metastasen eines malignen Melanoms oder einer Sarkominfiltration immunhistochemisch abgegrenzt werden. Das undifferenzierte Pankreaskarzinom mit osteoklastären Riesenzellen ist eine besondere Variante, die auch in Assoziation mit muzinös-zystischen Neoplasien auftreten kann und durch zahlreiche nichtneoplastische osteoklastäre Riesenzellen gekennzeichnet ist.

Abstract

Undifferentiated pancreatic carcinomas are rare anaplastic variants of ductal adenocarcinoma of the pancreas. They have to be distinguished immunohistochemically from metastases of malignant melanoma or an infiltrating sarcoma. An uncommon variant is undifferentiated pancreatic carcinoma with osteoclast-like giant cells. This variant can be associated with mucinous cystic neoplasms and is characterized by abundant non-neoplastic osteoclast-like giant cells.

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Correspondence to K. Peters.

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Peters, K., Klöppel, G. Undifferenzierte Pankreaskarzinome. Pathologe 26, 18–21 (2005). https://doi.org/10.1007/s00292-004-0731-4

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Schlüsselwörter

  • Pankreas
  • Undifferenziertes Karzinom
  • Osteoklastäre Riesenzellen
  • Diagnose

Keywords

  • Pancreas
  • Undifferentiated carcinoma
  • Osteoclast-like giant cells
  • Diagnosis