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Undifferenzierte Pankreaskarzinome

Der Sprung ins Chaos

Undifferentiated pancreatic carcinomas

Leap into chaos

  • Schwerpunkt: Pankreaspathologie
  • Published:
Der Pathologe Aims and scope Submit manuscript

Zusammenfassung

Die undifferenzierten Karzinome des Pankreas sind selten. Sie sind anaplastische Varianten des duktalen Adenokarzinoms des Pankreas. Differenzialdiagnostisch müssen sie von Metastasen eines malignen Melanoms oder einer Sarkominfiltration immunhistochemisch abgegrenzt werden. Das undifferenzierte Pankreaskarzinom mit osteoklastären Riesenzellen ist eine besondere Variante, die auch in Assoziation mit muzinös-zystischen Neoplasien auftreten kann und durch zahlreiche nichtneoplastische osteoklastäre Riesenzellen gekennzeichnet ist.

Abstract

Undifferentiated pancreatic carcinomas are rare anaplastic variants of ductal adenocarcinoma of the pancreas. They have to be distinguished immunohistochemically from metastases of malignant melanoma or an infiltrating sarcoma. An uncommon variant is undifferentiated pancreatic carcinoma with osteoclast-like giant cells. This variant can be associated with mucinous cystic neoplasms and is characterized by abundant non-neoplastic osteoclast-like giant cells.

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Authors and Affiliations

  1. Institut für Allgemeine Pathologie, Universität Kiel

    K. Peters & G. Klöppel

  2. Institut für Allgemeine Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Michaelisstraße 11, 24105, Kiel

    K. Peters

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  1. K. Peters
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  2. G. Klöppel
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Correspondence to K. Peters.

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Peters, K., Klöppel, G. Undifferenzierte Pankreaskarzinome. Pathologe 26, 18–21 (2005). https://doi.org/10.1007/s00292-004-0731-4

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  • DOI: https://doi.org/10.1007/s00292-004-0731-4

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