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Differenzialdiagnose basaloider Speicheldrüsentumoren

  • Schwerpunkt: Orale Pathologie/Pathologie der Speicheldrüsen
  • Published:
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Zusammenfassung

Die Differenzialdiagnose basaloider Speicheldrüsentumoren ist oft schwierig. Basaloid imponieren können kanalikuläre Adenome, Basalzell-Adenome und -adenokarzinome, adenoid-zystische Karzinome, polymorphe Low-grade-Adenokarzinome, seltener myoepitheliale Tumoren und epithelial-myoepitheliale Karzinome sowie basaloide Plattenepithelkarzinome. Bei sorgfältiger Aufarbeitung können diese Tumoren dennoch anhand histologischer Kriterien zuverlässig diagnostiziert werden. Die Immunhistochemie kann helfen, rein myoepitheliale Tumoren und basaloide Plattenepithelkarzinome sowie kanalikuläre Adenome zu erkennen. Die typischen morphologischen Befunde und die Kriterien für die Abgrenzung der Tumortypen werden vorgestellt und diskutiert.

Abstract

The diagnosis of basaloid tumors of the salivary glands can be challenging. In most cases, conventional histologic examination, if carried out meticulously, will be sufficient. Yet, immunohistochemistry will be of help for the definition of purely myoepithelial tumors, basaloid squamous cell carcinomas, and canalicular adenomas. The differential diagnosis of canalicular adenoma, basal cell adenoma and basal cell adenocarcinoma, adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, myoepithelial tumors, epithelial-myoepithelial carcinoma, and basaloid squamous cell carcinoma is discussed.

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  1. Institut für Oralpathologie, Zentrum Klinisch-theoretische Medizin I, Universitätsklinikum Eppendorf, Hamburg

    K. T. Jäkel & T. Löning

  2. Institut für Oralpathologie, Zentrum Klinisch-theoretische Medizin I, Universitätsklinikum Eppendorf, Martinistraße 52, 20246, Hamburg

    K. T. Jäkel

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  1. K. T. Jäkel
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  2. T. Löning
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Correspondence to K. T. Jäkel.

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Jäkel, K.T., Löning, T. Differenzialdiagnose basaloider Speicheldrüsentumoren. Pathologe 25, 46–55 (2004). https://doi.org/10.1007/s00292-003-0672-3

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  • DOI: https://doi.org/10.1007/s00292-003-0672-3

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