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Lymphadenom der Glandula parotis ohne Talgdrüsendifferenzierung

Immunhistochemische Untersuchungen

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Zusammenfassung

Bei einem 42-jährigen Patienten wurde ein seit 5 Jahren bestehender, 8 cm großer, gekapselter Tumor der Glandula parotis exstirpiert. Die histopathologische und immunhistochemische Untersuchung ergaben ein Lymphadenom ohne Talgdrüsendifferenzierung der Epithelkomponente mit ausschließlich soliden Epithelinseln und einem lymphatischen Stroma mit wenigen Lymphfollikeln und einem hohen Anteil IgG-positiver Plasmazellen. Die Histogenese der sehr seltenen Lymphadenome wird unter Berücksichtigung der Differenzialdiagnose zum Adenolymphom und der Darstellungen in der Literatur diskutiert.

Abstract

An encapsulated tumor measuring 8 cm was removed from the parotid gland in a 42-year-old man. The tumor had grown for about 5 years. The histopathological and immunohistochemical evaluation revealed a lymphadenoma without sebaceous differentiation of the epithelial component. The tumor consisted of exclusively solid epithelial islands and a lymphoid stroma with rare lymph follicles and abundant predominantly IgG plasma cells. The histogenesis of lymphadenomas is discussed in consideration of the differential diagnosis from Warthin's tumor and the data in the literature.

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Authors and Affiliations

  1. Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

    I. Bos & H. Merz

  2. Klinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

    S. Meyer

  3. Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 , Lübeck

    I. Bos

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  1. I. Bos
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Correspondence to I. Bos.

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Bos, I., Meyer, S. & Merz, H. Lymphadenom der Glandula parotis ohne Talgdrüsendifferenzierung. Pathologe 25, 73–78 (2004). https://doi.org/10.1007/s00292-003-0644-7

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  • DOI: https://doi.org/10.1007/s00292-003-0644-7

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