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Tumoren des endokrinen Pankreas

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Zusammenfassung

Die neuroendokrinen Tumoren des Pankreas sind insgesamt selten, gehören jedoch zu den häufigsten endokrinen Neoplasien des Abdominalraumes. In den meisten Fällen zeigen sie eine charakteristische Makro- und Histopathologie. Die WHO-Klassifikation unterscheidet auf der Basis von morphologischen, immunhistologischen und biologischen Kriterien zwischen gutdifferenzierten Tumoren mit benignem Verhalten oder fraglicher Dignität, gutdifferenzierten (niedrig malignen) Karzinomen und niedrigdifferenzierten (hoch malignen) Karzinomen. Die funktionellen Tumorentitäten, die der Klassifikation zugrunde liegen, werden kurz dargestellt und diskutiert.

Abstract

The neuroendocrine tumors of the pancreas are rare, but belong to the most common endocrine neoplasms of the abdomen. In most cases, they show a characteristic macroscopic and microscopic pathology. On the basis of morphological, immunohistological and biological criteria, the WHO classification distinguishes between well differentiated tumors with benign or uncertain behavior, well differentiated (low grade malignant) carcinomas and poorly differentiated (high grade malignant) carcinomas. The functional tumor entities on which the classification is based are briefly described and discussed.

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  1. Institut für Allgemeine Pathologie und Pathologische Anatomie, Universitätsklinikum Schleswig-Holstein, Campus Kiel

    G. Klöppel

  2. Institut für Allgemeine Pathologie und Pathologische Anatomie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Michaelisstraße 11, 24105 , Kiel

    G. Klöppel

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Klöppel, G. Tumoren des endokrinen Pankreas. Pathologe 24, 265–271 (2003). https://doi.org/10.1007/s00292-003-0634-9

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  • DOI: https://doi.org/10.1007/s00292-003-0634-9

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