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Nanoemulgel: a promising novel formulation for treatment of skin ailments

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Abstract

Nanoemulgel is an emanating drug delivery system particularly being explored in research and development of various topical formulations for both pharmaceutical and cosmeceutical applications. Nanoemulgel consists of emulsion, which can be water in oil or oil in water type, incorporated into gel base. The gel base is prepared using gelling agent which modifies emulsion into non-greasy, more stable, and viscous formulation. Incorporation of hydrophobic drugs in a topical gel formulation along with favorable patient compliance is not feasible, but nanoemulgel form of the same drug does that efficiently. Rationalized formulation development of nanoemulgel for various drugs could solve various problems related to drug solubility, stability and drug release associated with other topical formulations.

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Acknowledgements

Authors Dr. Keerti Jain and Ms. Surabhi Gupta acknowledge Department of Pharmaceuticals (DoP), Ministry of Chemicals and Fertilizers, Government of India, for their support. NIPER, Raebareli communication number for this manuscript is NIPER-R/Communication/175.

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  1. Brijesh Ojha and Vineet Kumar Jain have contributed equally to this work.

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  1. Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi, India

    Brijesh Ojha, Vineet Kumar Jain, Sushama Talegaonkar & Keerti Jain

  2. Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER) – Raebareli, Lucknow, India

    Surabhi Gupta & Keerti Jain

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Ojha, B., Jain, V.K., Gupta, S. et al. Nanoemulgel: a promising novel formulation for treatment of skin ailments. Polym. Bull. 79, 4441–4465 (2022). https://doi.org/10.1007/s00289-021-03729-3

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