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Polyurethanes in cardiovascular prosthetics

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Abstract

Polyurethane has become a popular material in biomedical industry because of its good mechanical properties as well as biocompatibility and hemocompatibility. However, the material degrades during a long-term functioning of polyurethane grafts. To increase biostability, novel polyurethanes with a siloxane segment, polycarbonate polyurethanes, and nanocomposite polyurethanes are offered. Along with novel polyurethanes, modern tissue engineering technologies are well applicable for manufacture of the polyurethane products with unique properties. Different polyurethanes and modern technologies for producing cardiovascular grafts of polyurethane are discussed.

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Funding

This work was supported by the Russian Science Foundation (Grant no. 17-75-30009).

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Authors and Affiliations

  1. Department of Vascular and Hybrid Surgery, Meshalkin National Medical Research Center, Ministry of Public Health of the Russian Federation, Ul. Rossiiskaya 21 Apt. 35, Novosibirsk, 630055, Russia

    Alexander A. Gostev, Andrei A. Karpenko & Pavel P. Laktionov

  2. Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Pr. Lavrentieva 8, Novosibirsk, 630090, Russia

    Pavel P. Laktionov

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  1. Alexander A. Gostev
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Correspondence to Alexander A. Gostev.

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Gostev, A.A., Karpenko, A.A. & Laktionov, P.P. Polyurethanes in cardiovascular prosthetics. Polym. Bull. 75, 4311–4325 (2018). https://doi.org/10.1007/s00289-017-2266-x

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