Skip to main content
SpringerLink
Log in

Antimicrobial nitrile gloves coated by electrospun trimethylated chitosan-loaded polyvinyl alcohol ultrafine fibers

  • Original Paper
  • Published:
Polymer Bulletin Aims and scope Submit manuscript

Abstract

The electrospun trimethylated chitosan (TMC)-loaded polyvinyl alcohol (PVAl) ultrafine fibers with diameters of 70–175 nm were successfully coated on nitrile gloves. The fibers were produced using aqueous TMC mixed with PVAl solutions with a fiber collection distance set at 12 cm. The applied electrical voltages (12, 14, 16, 18, and 20 kV) and the ratios between TMC and PVAl (2:10 and 4:8 % w/v) were varied. It was found that they did not affect the diameter of the fibers, but they did the uniformity of the fibers. Scanning electron microscope (SEM) images revealed that the only condition giving the uniform fibers was 4 % w/v TMC blended with 8 % w/v PVAl spinning mixture and a voltage of 16 kV. The fiber-coated gloves showed the antimicrobial characteristics against the Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii) and yeast (Candida albicans), the improved surface roughness from 429 to 511 μm2, and the enhanced wettability.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. McKeen LW (2012) Permeability properties of plastics and elastomers. William Andrew Publishing, USA

    Google Scholar 

  2. Daeschlein G, Kramer A, Arnold A, Ladwig A, Seabrook GR, Edmiston CE (2011) Evaluation of an innovative antimicrobial surgical glove technology to reduce the risk of microbial passage following intraoperative perforation. Am J Infect Control 39(2):98–103. doi:10.1016/j.ajic.2010.05.026

    Article  Google Scholar 

  3. Reitzel RA, Dvorak TL, Hachem RY, Fang X, Jiang Y, Raad I (2009) Efficacy of novel antimicrobial gloves impregnated with antiseptic dyes in preventing the adherence of multidrug-resistant nosocomial pathogens. Am J Infect Control 37(4):294–300. doi:10.1016/j.ajic.2008.07.003

    Article  Google Scholar 

  4. Yorsaeng S, Pornsunthorntawee O, Rujiravanit R (2012) Preparation and characterization of chitosan-coated DBD plasma-treated natural rubber latex medical surgical gloves with antibacterial activities. Plasma Chem Plasma Process 32:1275–92. doi:10.1007/s11090-012-9405-9

  5. Kanjanathaworn N, Kaewsaneha C, Polpanich D, Jangpatarapongsa K, Tangboriboonrat P (2012) Composite nanoparticles on the natural rubber latex glove for reduction of surface friction and cytotoxicity. Polym Polym Compos 20(1–2):197–200

    CAS  Google Scholar 

  6. Kanjanathaworn N, Polpanich D, Jangpatarapongsa K, Tangboriboonrat P (2013) Reduction of cytotoxicity of natural rubber latex film by coating with PMMA-chitosan nanoparticles. Carbohyd Polym 97(1):52–58. doi:10.1016/j.carbpol.2012.12.078

    Article  CAS  Google Scholar 

  7. Ramakrishna S, Fujihara K, Teo W, Lim T, Ma Z (2005) An introduction to electrospinning and nanofibers. World Scientific Publishing, Singapore

    Book  Google Scholar 

  8. Kontogiannopoulos KN, Assimopoulou AN, Tsivintzelis I, Panayiotou C, Papageorgiou VP (2011) Electrospun fiber mats containing shikonin and derivatives with potential biomedical applications. Int J Pharm 409(1–2):216–228. doi:10.1016/j.ijpharm.2011.02.004

    Article  CAS  Google Scholar 

  9. Fletcher BL, McKnight TE, Fowlkes JD, Allison DP, Simpson ML, Doktycz MJ (2007) Controlling the dimensions of carbon nanofiber structures through the electropolymerization of pyrrole. Synth Met 157(6–7):282–289. doi:10.1016/j.synthmet.2007.03.004

    Article  CAS  Google Scholar 

  10. Zheng L, Zhu J (2003) Study on antimicrobial activity of chitosan with different molecular weights. Carbohyd Polym 54(4):527–530. doi:10.1016/j.carbpol.2003.07.009

    Article  CAS  Google Scholar 

  11. Raafat D, von Bargen K, Haas A, Sahl H-G (2008) Insights into the mode of action of chitosan as an antibacterial compound. Appl Environ Microbial 74(12):3764–3773. doi:10.1128/AEM.00453-08

    Article  CAS  Google Scholar 

  12. Kong M, Chen XG, Xing K, Park HJ (2010) Antimicrobial properties of chitosan and mode of action: a state of the art review. Int J Food Microbiol 144(1):51–63. doi:10.1016/j.ijfoodmicro.2010.09.012

    Article  CAS  Google Scholar 

  13. Bégin A, van Calsteren M (1999) Antimicrobial films produced from chitosan. Int J Biol Macromol 26(1):63–67. doi:10.1016/S0141-8130(99)00064-1

    Article  Google Scholar 

  14. El-tahlawy KF, El-bendary MA, Elhendawy AG, Hudson SM (2005) The antimicrobial activity of cotton fabrics treated with different crosslinking agents and chitosan. Carbohyd Polym 60:421–430. doi:10.1016/j.carbpol.2005.02.019

    Article  CAS  Google Scholar 

  15. VandeVord PJ, Matthew HW, DeSilva SP, Mayton L, Wu B, Wooley PH (2002) Evaluation of the biocompatibility of a chitosan scaffold in mice. J Biomed Mater Res 59(3):585–590. doi:10.1002/jbm.1270

    Article  CAS  Google Scholar 

  16. Chen X, Liu C, Liu C, Meng X, Lee CM, Park H (2006) Preparation and biocompatibility of chitosan microcarriers as biomaterial. Biochem Eng J 27:269–274. doi:10.1016/j.bej.2005.08.021

    Article  CAS  Google Scholar 

  17. de Souza Costa-Júnior E, Pereira MM, Mansur HS (2009) Properties and biocompatibility of chitosan films modified by blending with PVA and chemically crosslinked. J Mater Sci Mater Med 20(2):553–561. doi:10.1007/s10856-008-3627-7

    Article  Google Scholar 

  18. Thanou M, Florea BI, Geldof M, Junginger HE, Borchard G (2002) Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. Biomaterials 23(1):153–159. doi:10.1016/S0142-9612(01)00090-4

    Article  CAS  Google Scholar 

  19. Ignatova M, Starbova K, Markova N, Manolova N, Rashkov I (2006) Electrospun nano-fibre mats with antibacterial properties from quaternised chitosan and poly(vinyl alcohol). Carbohydr Res 341(12):2098–2107. doi:10.1016/j.carres.2006.05.006

    Article  CAS  Google Scholar 

  20. Ignatova M, Manolova N, Rashkov I (2007) Novel antibacterial fibers of quaternized chitosan and poly(vinyl pyrrolidone) prepared by electrospinning. Eur Polym J 43:1112–1122. doi:10.1016/j.eurpolymj.2007.01.012

    Article  CAS  Google Scholar 

  21. Alipour SM, Nouri M, Mokhtari J, Bahrami SH (2009) Electrospinning of poly(vinyl alcohol)-water-soluble quaternized chitosan derivative blend. Carbohydr Res 344(18):2496–2501. doi:10.1016/j.carres.2009.10.004

    Article  CAS  Google Scholar 

  22. Chang W, Ma G, Yang D, Su D, Song G, Nie J (2010) Electrospun ultrafine composite fibers from organic-soluble chitosan and poly(ethylene oxide). J Appl Polym Sci 117(4):2113–2120. doi:10.1002/app.31911

    Article  CAS  Google Scholar 

  23. Deng H, Lin P, Xin S, Huang R, Li W, Du Y, Zhou X, Yang J (2012) Quaternized chitosan-layered silicate intercalated composites based nanofibrous mats and their antibacterial activity. Carbohyd Polym 89(2):307–313. doi:10.1016/j.carbpol.2012.02.009

    Article  CAS  Google Scholar 

  24. Hallensleben ML (2000) Ullmann’s encyclopedia of industrial chemistry. Wiley-VCH, USA

    Google Scholar 

  25. Verheul RJ, Amidi M, Wal S, Riet E, Jiskoot W, Hennink WE (2008) Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan. Biomaterials 29:3642–3649. doi:10.1016/j.biomaterials.2008.05.026

    Article  CAS  Google Scholar 

  26. Beachley V, Wen X (2009) Effect of electrospinning parameters on the nanofiber diameter and length. Mater Sci Eng C Mater Biol Appl 29(3):663–668. doi:10.1016/j.msec.2008.10.037

    Article  CAS  Google Scholar 

  27. Wongsomboon P, Sunintaboon P, Tangboriboonrat P, Vongsetskul T (2013) Fabrication of powder-free natural rubber gloves coated by electrospinning quaternized chitosan-loaded ultrafine fibers. Faculty of Science, Burapha University. http://www.sci.buu.ac.th/research/uploads/download/anc/proceedings.paccon2013.pdf. Accessed 29 Oct 2013

  28. Vongsetskul T, Kongjumnean P, Sunintaboon P, Rangkupan R, Tangboriboonrat P (2012) Electrospun composite fibers of polyvinylpyrrolidone with embedded poly(methyl methacrylate)–polyethyleneimine core–shell particles. Polym Bull 69:1115–1123. doi:10.1007/s00289-012-0870-3

    Article  CAS  Google Scholar 

  29. Koohmareh GA, Hajian M, Fallahi H (2011) Graft copolymerization of styrene from poly(vinyl alcohol) via RAFT process. Int J Polym Sci 2011:190349. doi:10.1155/2011/190349

    Article  Google Scholar 

  30. Tan H, Ma R, Lin C, Liu Z, Tang T (2013) Quaternized chitosan as an antimicrobial agent: antimicrobial activity, mechanism of action and biomedical applications in orthopedics. Int J Mol Sci 14(1):1854–1869. doi:10.3390/ijms14011854

    Article  CAS  Google Scholar 

  31. Jia Z, Shen D, Xu W (2001) Synthesis and antibacterial activities of quaternary ammonium salt of chitosan. Carbohydr Res 333(1):1–6. doi:10.1016/S0008-6215(01)00112-4

    Article  CAS  Google Scholar 

Download references

Acknowledgments

Research grants from Mahidol University Faculty of Science, Thailand Ministry of Science and Technology, and The Thailand Research Fund (TRF)/Mahidol University (TRG5680070) to T. V. and from TRF/Commission on Higher Education to P. T. (RTA5480007) are gratefully acknowledged.

Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Road, Ratchathewi, Bangkok, 10400, Thailand

    Thammasit Vongsetskul, Preeyaporn Wongsomboon, Panya Sunintaboon & Pramuan Tangboriboonrat

  2. Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, 2 Prannok Road, Bangkok-Noi, Bangkok, 10700, Thailand

    Srisurang Tantimavanich

Authors
  1. Thammasit Vongsetskul
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Preeyaporn Wongsomboon
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Panya Sunintaboon
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Srisurang Tantimavanich
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Pramuan Tangboriboonrat
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Thammasit Vongsetskul.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 131 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vongsetskul, T., Wongsomboon, P., Sunintaboon, P. et al. Antimicrobial nitrile gloves coated by electrospun trimethylated chitosan-loaded polyvinyl alcohol ultrafine fibers. Polym. Bull. 72, 2285–2296 (2015). https://doi.org/10.1007/s00289-015-1404-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00289-015-1404-6

Keywords

Search

Navigation