Journal of Mathematical Biology

, Volume 56, Issue 6, pp 893–896 | Cite as

Mathematical challenges in integrative physiology

  • B. S. BrookEmail author
  • S. L. Waters


Asthma Airway Smooth Muscle Boolean Network Airway Smooth Muscle Cell Airway Wall 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gavaghan, D.J., Simpson, A.C., Lloyd, S., MacRandal, D.F., Boyd, D.R.S.: Towards a grid infrastructure to support integrative approaches to biological research. Phil. Trans. R. Soc. A 363, 1829–1841 (2005)CrossRefGoogle Scholar
  2. 2.
    Butcher, E.C., Berg, E.L., Kunkel, E.J.: Systems biology in drug discovery. Nature Biotech. 2, 1253–1259 (2004)CrossRefGoogle Scholar
  3. 3.
    Ideker, T., Galitski, T., Hood, L.: A new approach to decoding life: systems biology. Annu. Rev. Genomics Hum. Genet. 2, 343–372 (2001)CrossRefGoogle Scholar
  4. 4.
    Hunter, P., Nielsen, P.: A strategy for integrative computational physiology. Physiology 20, 316–325 (2005)CrossRefGoogle Scholar
  5. 5.
    Hunter, P., Robbins, P., Noble, D.: The IUPS human physiome project. Eur. J. Physiol. 445, 9 (2002)CrossRefGoogle Scholar
  6. 6.
    Hunter, P., Smith, N., Fernandez, J., Tawhai, M.: Integration from proteins to organs: the IUPS Physiome Project. Mech. Ageing Dev. 126, 187–192 (2005)CrossRefGoogle Scholar
  7. 7.
    The STEP consortium. Seeding the Europhysiome: A Roadmap to the Virtual Physiological Human. On-line 5th July 2007.
  8. 8.
    The Heart Physiome Project.

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.School of Mathematical SciencesUniversity Park, University of NottinghamNottinghamUK
  2. 2.Oxford Centre for Industrial and Applied MathematicsMathematical InstituteOxfordUK

Personalised recommendations