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Probiotic Formulations: A Patent Landscaping Using the Text Mining Approach

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Abstract

The outstanding research outcomes and registrations of myriads of probiotic strains have flooded the health market with various innovative probiotic-based products and their patents. The study of patented formulations of probiotics can give an overall insight into its existing application. A landscaping review of patents for probiotic-based preparations is presented in the current work. The patent search was performed over commercially available patent databased and analysis tool—PatSeer Pro®. Search strings containing words "Formulation" and "Composition" resulted in more than 3700 patents. Landscaping review of 400 + patents from the last 20 years (2000–2020) was performed using the Text-Mining approach. Text-Mining helped to identify 19 technological clusters which represent these patents. These clusters include the patents of probiotic preparations on animal feed, human food, cosmetics, antimicrobial, antidiabetic, arthritis, etc. A review of this massive number of patents unveiled many exciting preparations. Probiotic-based innovative products for depression, diabetes, Parkinson's, tumor, acne, and animal husbandry are reviewed comprehensively. The present work also unravels a few new-flanged products like probiotic layered condoms, products for acute alcoholism, and traditional Chinese medicine with probiotics. The patent landscape of probiotic-based preparations has presented a whole scenario of probiotic-based preparations. It has also revealed many unexplored areas where innovation can be excelled.

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Acknowledgements

Authors are grateful to CHARUSAT IPR Cell for providing training and access to PatSeer®—Patent Search and Analysis Tool.

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Authors and Affiliations

  1. Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology (CHARUSAT), CHARUSAT Campus, Changa, 388421, India

    Swayamprakash Patel, Ashish D. Patel, Umang H. Shah, Mehul M. Patel, Nilay D. Solanki & Meet J. Patel

  2. Research and Development (Clinical), Meteroic Biopharmaceuticals, Ahmedabad, India

    Mruduka S. Patel

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  1. Swayamprakash Patel
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  2. Mruduka S. Patel
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Contributions

SKP: Conceptualization of studies of patents on probiotic formulations. Investigation: Detailed study of each patent on probiotic formulations was performed. Original draft was also prepared. MSP: Text-Mining methodology for handling huge data on probiotics patents is developed. Hierarchical Cluster Analysis was performed. ADP: Overall supervision of work and suggestions on topic inclusions were provided. UHS: Fine visualizations were prepared for the review article. MMP: Review and editing of article for significant errors and corrections. NDS: Validation of facts and finding from the selected patents was performed. MJP: Formal Analysis: Statistical analysis of data is performed.

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Patel, S., Patel, M.S., Patel, A.D. et al. Probiotic Formulations: A Patent Landscaping Using the Text Mining Approach. Curr Microbiol 79, 152 (2022). https://doi.org/10.1007/s00284-022-02836-2

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