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Characterization and Genome Analysis of a Zearalenone-Degrading Bacillus velezensis Strain ANSB01E

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Abstract

Zearalenone, a nonsteroidal estrogenic mycotoxin mainly produced by Fusarium species, causes reproductive disorders and hyperestrogenic syndromes in animals and humans. The bacterial strain Bacillus velezensis ANSB01E, isolated from chicken cecal content, was capable of effectively degrading zearalenone in both liquid medium and mouldy corn. Moreover, Bacillus velezensis ANSB01E exhibited good antimicrobial activities against animal pathogenic bacteria, including Escherichia coli, Staphylococcus aureus, and Salmonella spp. Genome-based analysis revealed the presence of genes coding peroxiredoxin and alpha/beta hydrolase in Bacillus velezensis ANSB01E, which may be involved in zearalenone degradation. The study on the genome provides insights into the zearalenone degradation mechanisms and advances the potential application of Bacillus velezensis ANSB01E in food and feed industry.

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Acknowledgements

This work was supported by the grants from National Natural Science Foundation of China (Project No.31772637).

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Author notes

  1. Yongpeng Guo and Jianchuan Zhou have contributed equally to this work

Authors and Affiliations

  1. State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People’s Republic of China

    Yongpeng Guo, Jianchuan Zhou, Yu Tang, Qiugang Ma, Jianyun Zhang, Cheng Ji & Lihong Zhao

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  1. Yongpeng Guo
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  2. Jianchuan Zhou
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  3. Yu Tang
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  7. Lihong Zhao
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Correspondence to Lihong Zhao.

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Guo, Y., Zhou, J., Tang, Y. et al. Characterization and Genome Analysis of a Zearalenone-Degrading Bacillus velezensis Strain ANSB01E. Curr Microbiol 77, 273–278 (2020). https://doi.org/10.1007/s00284-019-01811-8

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  • DOI: https://doi.org/10.1007/s00284-019-01811-8

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