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Nannochloropsis sp. and Spirulina sp. as a Source of Antifungal Compounds to Mitigate Contamination by Fusarium graminearum Species Complex

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Abstract

Phenolic (free, conjugated and bound) and carotenoid extracts from microalgae Nannochloropsis sp. and Spirulina sp. were investigated regarding their potential to mitigate contamination by Fusarium complex fungal pathogens. Free phenolic acid extracts from both microalgae were the most efficient, promoting the lowest mycelial growth rates of 0.51 cm day− 1 (Spirulina sp.) and 0.78 cm day− 1 (Nannochloropsis sp.). An experiment involving natural free phenolic acid extracts and synthetic solutions was carried out based on the natural phenolic acid profile. The results revealed that the synthetic mixtures of phenolic acids from both microalgae were less efficient than the natural extracts at inhibiting fungal growth, indicating that no purification is required. The half-maximal effective concentration (EC50) values of 49.6 μg mL− 1 and 33.9 μg mL− 1 were determined for the Nannochloropsis and Spirulina phenolic acid extracts, respectively. The use of phenolic extracts represents a new perspective regarding the application of compounds produced by marine biotechnology to prevent Fusarium species contamination.

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Acknowledgements

The authors thank the Programa de Pós-Graduação em Engenharia e Ciência de Alimentos (FURG) and CNPq-Conselho Nacional de Desenvolvimento Científico e Tecnológico for supported this study by the Project 472633/2012.

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Author notes

  1. Priscila Tessmer Scaglioni

    Present address: Programa de Pós-Graduação em Bioquímica e Bioprospecção, Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Laboratório de Controle de Contaminantes em Biomateriais, Universidade Federal de Pelotas (UFPel), Avenida Eliseu Maciel, S/N, Capão do Leão, Pelotas, RS, CEP: 96160-000, Brazil

Authors and Affiliations

  1. Programa de Pós-Graduação em Engenharia e Ciência de Alimentos, Escola de Química e Alimentos, Laboratório de Micotoxinas e Ciência de Alimentos, Universidade Federal do Rio Grande (FURG), Avenida Itália, km 8, Bairro Carreiros, Rio Grande, RS, CEP: 96203-900, Brazil

    Priscila Tessmer Scaglioni, Andressa Cunha Lemos & Eliana Badiale-Furlong

  2. Universidade Federal do Rio Grande (FURG), Santo Antônio da Patrulha, RS, CEP: 95500-000, Brazil

    Fernanda Arnhold Pagnussatt

  3. Universidade Federal de Viçosa (UFV), Viçosa, MG, Brazil

    Camila Primieri Nicolli & Emerson M. Del Ponte

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  1. Priscila Tessmer Scaglioni
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Correspondence to Priscila Tessmer Scaglioni.

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Scaglioni, P.T., Pagnussatt, F.A., Lemos, A.C. et al. Nannochloropsis sp. and Spirulina sp. as a Source of Antifungal Compounds to Mitigate Contamination by Fusarium graminearum Species Complex. Curr Microbiol 76, 930–938 (2019). https://doi.org/10.1007/s00284-019-01663-2

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